Skip to main content

Table 2 Genotypic and allelic frequencies and the risk of CAD and IS

From: Association of polymorphisms in the MAFB gene and the risk of coronary artery disease and ischemic stroke: a case–control study

Genotype or allele

Control (%)

CAD (%)

IS (%)

CAD

IS

n = 539

n = 525

n = 540

OR (95 % CI)

P

OR (95 % CI)

P

rs2902940

GG

74(13.7)

47(9.0)

47(8.7)

1

 

1

 

GA

225(41.8)

220(41.9)

242(44.8)

1.48(0.97–2.26)

0.071

1.76(1.14–2.71)

0.011

AA

240(44.5)

258(49.1)

251(46.5)

1.63(1.07–2.48)

0.023

1.69(1.09–2.61)

0.017

P

 

0.038

0.032

    

G

373(34.6)

314(29.9)

336(31.1)

1

   

A

705(65.4)

736(70.1)

744(68.9)

1.22(1.01–1.48)

0.036

1.18(0.98–1.41)

0.078

P

 

0.021

0.084

    

HWE(P)

0.071

0.992

0.290

    

GG

74(13.7)

47(9.0)

47(8.7)

1

 

1

 

GA + AA

465(86.3)

478(91.0)

493(91.3)

1.56(1.04–2.32)

0.030

1.72(1.14–2.60)

0.010

P

 

0.014

0.009

    

AA

243(45.1)

258(49.1)

251(46.5)

1

 

1

 

GA + GG

296(54.9)

267(50.9)

289(53.5)

0.85(0.66–1.09)

0.208

0.93(0.72–1.20)

0.559

P

 

0.185

0.645

    

rs6102059

CC

121(22.4)

123(23.4)

108(20.0)

1

 

1

 

CT

249(46.2)

261(49.7)

280(51.9)

1.01(0.73–1.39)

0.958

1.19(0.85–1.66)

0.303

TT

169(31.4)

141(26.9)

152(28.1)

0.78(0.55–1.11)

0.170

0.93(0.64–1.33)

0.676

P

 

0.267

0.178

    

C

491(44.5)

507(48.3)

496(45.9)

    

T

587(54.5)

543(51.7)

584(54.1)

0.90(0.76–1.07)

0.233

0.99(0.83–1.17)

0.891

P

 

0.206

0.860

    

HWE(P)

0.111

0.917

0.307

    

CC

129(23.9)

123(23.4)

108(20.0)

1

 

1

 

CT + TT

410(76.1)

402(76.6)

432(80.0)

0.96(0.71–1.28)

0.764

1.13(0.83–1.54)

0.443

P

 

0.847

0.119

    

TT

169(31.4)

141(26.9)

152(28.1)

1

 

1

 

CT + CC

370(68.6)

384(73.1)

388(71.9)

1.29(0.98–1.69)

0.074

1.22(0.93–1.61)

0.155

P

 

0.107

0.249

    
  1. HWE Hardy-Weinberg equilibrium, CAD coronary artery disease, IS ischemic stroke