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Table 2 Genotypic and allelic frequencies and the risk of CAD and IS

From: Association of polymorphisms in the MAFB gene and the risk of coronary artery disease and ischemic stroke: a case–control study

Genotype or allele Control (%) CAD (%) IS (%) CAD IS
n = 539 n = 525 n = 540 OR (95 % CI) P OR (95 % CI) P
rs2902940
GG 74(13.7) 47(9.0) 47(8.7) 1   1  
GA 225(41.8) 220(41.9) 242(44.8) 1.48(0.97–2.26) 0.071 1.76(1.14–2.71) 0.011
AA 240(44.5) 258(49.1) 251(46.5) 1.63(1.07–2.48) 0.023 1.69(1.09–2.61) 0.017
P   0.038 0.032     
G 373(34.6) 314(29.9) 336(31.1) 1    
A 705(65.4) 736(70.1) 744(68.9) 1.22(1.01–1.48) 0.036 1.18(0.98–1.41) 0.078
P   0.021 0.084     
HWE(P) 0.071 0.992 0.290     
GG 74(13.7) 47(9.0) 47(8.7) 1   1  
GA + AA 465(86.3) 478(91.0) 493(91.3) 1.56(1.04–2.32) 0.030 1.72(1.14–2.60) 0.010
P   0.014 0.009     
AA 243(45.1) 258(49.1) 251(46.5) 1   1  
GA + GG 296(54.9) 267(50.9) 289(53.5) 0.85(0.66–1.09) 0.208 0.93(0.72–1.20) 0.559
P   0.185 0.645     
rs6102059
CC 121(22.4) 123(23.4) 108(20.0) 1   1  
CT 249(46.2) 261(49.7) 280(51.9) 1.01(0.73–1.39) 0.958 1.19(0.85–1.66) 0.303
TT 169(31.4) 141(26.9) 152(28.1) 0.78(0.55–1.11) 0.170 0.93(0.64–1.33) 0.676
P   0.267 0.178     
C 491(44.5) 507(48.3) 496(45.9)     
T 587(54.5) 543(51.7) 584(54.1) 0.90(0.76–1.07) 0.233 0.99(0.83–1.17) 0.891
P   0.206 0.860     
HWE(P) 0.111 0.917 0.307     
CC 129(23.9) 123(23.4) 108(20.0) 1   1  
CT + TT 410(76.1) 402(76.6) 432(80.0) 0.96(0.71–1.28) 0.764 1.13(0.83–1.54) 0.443
P   0.847 0.119     
TT 169(31.4) 141(26.9) 152(28.1) 1   1  
CT + CC 370(68.6) 384(73.1) 388(71.9) 1.29(0.98–1.69) 0.074 1.22(0.93–1.61) 0.155
P   0.107 0.249     
  1. HWE Hardy-Weinberg equilibrium, CAD coronary artery disease, IS ischemic stroke