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Table 3 Stratified analysis between rs2902940 genotype and the risk of CAD and IS

From: Association of polymorphisms in the MAFB gene and the risk of coronary artery disease and ischemic stroke: a case–control study

Factors

CAD

IS

OR (95 % CI)

P interaction

OR (95 % CI)

P interaction

GG

GA + AA

P

GG

GA + AA

P

Gender

Male

1

1.76(1.11–2.80)

0.016

 

1

1.83(1.14–2.93)

0.012

 

Female

1

0.82(0.33–2.01)

0.658

0.366

1

1.39(0.50–3.89)

0.531

0.229

Age, year

≤60

1

2.28(1.16–4.49)

0.017

 

1

2.76(1.39–5.41)

0.004

 

>60

1

1.21(0.73–2.01)

0.460

0.326

1

1.39(0.82–2.36)

0.225

0.272

BMI, kg/m2

≤24

1

1.17(0.70–1.95)

0.549

 

1

1.46(0.85–2.51)

0.171

 

>24

1

2.77(1.38–5.57)

0.004

0.002

1

2.73(1.40–5.33)

0.003

0.001

Smoking

No

1

1.35(0.75–2.43)

0.313

 

1

1.17(0.67–2.03)

0.578

 

Yes

1

1.81(0.97–3.37)

0.061

0.073

1

2.72(1.40–5.31)

0.003

0.064

Alcohol

No

 

1.18(0.68–2.05)

0.552

 

1

1.41(0.83–2.42)

0.207

 

Yes

 

1.96(1.02–3.78)

0.044

0.904

1

2.53(1.26–5.07)

0.009

0.113

Hypertension

No

1

1.29(0.75–2.23)

0.360

 

1

1.57(0.88–2.78)

0.126

 

Yes

1

2.11(1.09–4.08)

0.027

<0.001

1

2.10(1.12–3.92)

0.020

<0.001

Hyperlipidemia

No

1

1.50(0.91–2.49)

0.112

 

1

2.39(1.33–4.29)

0.004

 

Yes

1

1.73(0.87–3.43)

0.118

0.082

1

1.33(0.70–2.51)

0.388

0.321

T2DM

No

1

1.57(0.90–2.73)

0.110

 

1

1.62(0.93–2.82)

0.090

 

Yes

1

3.67(1.76–7.67)

0.001

<0.001

1

3.22(1.47–7.05)

0.003

0.002

  1. CAD coronary artery disease, IS ischemic stroke, T2DM type 2 diabetes mellitus