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Table 3 Stratified analysis between rs2902940 genotype and the risk of CAD and IS

From: Association of polymorphisms in the MAFB gene and the risk of coronary artery disease and ischemic stroke: a case–control study

Factors CAD IS
OR (95 % CI) P interaction OR (95 % CI) P interaction
GG GA + AA P GG GA + AA P
Gender
Male 1 1.76(1.11–2.80) 0.016   1 1.83(1.14–2.93) 0.012  
Female 1 0.82(0.33–2.01) 0.658 0.366 1 1.39(0.50–3.89) 0.531 0.229
Age, year
≤60 1 2.28(1.16–4.49) 0.017   1 2.76(1.39–5.41) 0.004  
>60 1 1.21(0.73–2.01) 0.460 0.326 1 1.39(0.82–2.36) 0.225 0.272
BMI, kg/m2
≤24 1 1.17(0.70–1.95) 0.549   1 1.46(0.85–2.51) 0.171  
>24 1 2.77(1.38–5.57) 0.004 0.002 1 2.73(1.40–5.33) 0.003 0.001
Smoking
No 1 1.35(0.75–2.43) 0.313   1 1.17(0.67–2.03) 0.578  
Yes 1 1.81(0.97–3.37) 0.061 0.073 1 2.72(1.40–5.31) 0.003 0.064
Alcohol
No   1.18(0.68–2.05) 0.552   1 1.41(0.83–2.42) 0.207  
Yes   1.96(1.02–3.78) 0.044 0.904 1 2.53(1.26–5.07) 0.009 0.113
Hypertension
No 1 1.29(0.75–2.23) 0.360   1 1.57(0.88–2.78) 0.126  
Yes 1 2.11(1.09–4.08) 0.027 <0.001 1 2.10(1.12–3.92) 0.020 <0.001
Hyperlipidemia
No 1 1.50(0.91–2.49) 0.112   1 2.39(1.33–4.29) 0.004  
Yes 1 1.73(0.87–3.43) 0.118 0.082 1 1.33(0.70–2.51) 0.388 0.321
T2DM
No 1 1.57(0.90–2.73) 0.110   1 1.62(0.93–2.82) 0.090  
Yes 1 3.67(1.76–7.67) 0.001 <0.001 1 3.22(1.47–7.05) 0.003 0.002
  1. CAD coronary artery disease, IS ischemic stroke, T2DM type 2 diabetes mellitus
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Lipids in Health and Disease

ISSN: 1476-511X