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Table 6 Effect of the genotypes on serum lipid levels

From: Association of polymorphisms in the MAFB gene and the risk of coronary artery disease and ischemic stroke: a case–control study

Group/Genotype TC (mmol/L) TG (mmol/L) HDL-C (mmol/L) LDL-C (mmol/L) ApoAI (g/L) ApoB (g/L) ApoAI/ApoB
Control
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GG 4.64 ± 0.14 1.10(0.93) 1.56 ± 0.06 2.74 ± 0.11 1.24 ± 0.03 0.88 ± 0.03 1.45 ± 0.21
GA 4.78 ± 0.08 1.16(0.96) 1.47 ± 0.03 2.82 ± 0.06 1.19 ± 0.02 0.89 ± 0.02 1.56 ± 0.12
AA 4.63 ± 0.08 1.01(0.67) 1.46 ± 0.03 2.77 ± 0.06 1.14 ± 0.02 0.90 ± 0.02 1.35 ± 0.11
P 0.346 0.222 0.312 0.765 0.018 0.838 0.440
GG 4.64 ± 0.14 1.10(0.93) 1.56 ± 0.06 2.74 ± 0.11 1.24 ± 0.03 0.88 ± 0.03 1.45 ± 0.21
GA + AA 4.71 ± 0.05 1.08(0.79) 1.45 ± 0.02 2.79 ± 0.04 1.16 ± 0.01 0.89 ± 0.01 1.45 ± 0.08
P 0.673 0.680 0.136 0.653 0.024 0.615 0.986
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CC 4.70 ± 0.11 1.13(0.85) 1.45 ± 0.04 2.78 ± 0.08 1.14 ± 0.03 0.89 ± 0.02 1.29 ± 0.16
CT 4.69 ± 0.08 1.02(0.78) 1.48 ± 0.03 2.77 ± 0.06 1.17 ± 0.02 0.89 ± 0.02 1.55 ± 0.11
TT 4.71 ± 0.09 1.13(0.85) 1.51 ± 0.04 2.81 ± 0.07 1.20 ± 0.02 0.90 ± 0.02 1.41 ± 0.14
P 0.976 0.919 0.593 0.928 0.235 0.857 0.396
CC 4.70 ± 0.11 1.13(0.85) 1.45 ± 0.04 2.78 ± 0.08 1.14 ± 0.03 0.89 ± 0.02 1.29 ± 0.16
CT + TT 4.70 ± 0.06 1.05(0.81) 1.49 ± 0.02 2.78 ± 0.05 1.18 ± 0.01 0.89 ± 0.01 1.50 ± 0.09
P 0.943 0.733 0.427 0.971 0.146 0.972 0.268
CAD
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GG 4.60 ± 0.17 1.12(0.59) 1.39 ± 0.07 2.59 ± 0.13 1.16 ± 0.04 0.87 ± 0.04 1.39 ± 0.10
GA 4.67 ± 0.08 1.18(0.80) 1.49 ± 0.03 2.75 ± 0.06 1.17 ± 0.02 0.91 ± 0.02 1.41 ± 0.04
AA 4.56 ± 0.07 1.23(0.83) 1.41 ± 0.03 2.70 ± 0.06 1.14 ± 0.02 0.90 ± 0.02 1.34 ± 0.04
P 0.608 0.440 0.153 0.486 0.511 0.509 0.440
GG 4.60 ± 0.17 1.12(0.59) 1.39 ± 0.07 2.59 ± 0.13 1.16 ± 0.04 0.87 ± 0.04 1.39 ± 0.10
GA + AA 4.61 ± 0.05 1.21(0.80) 1.45 ± 0.02 2.73 ± 0.04 1.15 ± 0.01 0.90 ± 0.01 1.37 ± 0.03
P 0.954 0.317 0.427 0.307 0.919 0.312 0.877
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CC 4.64 ± 0.11 1.18(0.81) 1.46 ± 0.04 2.76 ± 0.08 1.16 ± 0.03 0.90 ± 0.02 1.37 ± 0.06
CT 4.56 ± 0.07 1.17(0.66) 1.45 ± 0.03 2.65 ± 0.06 1.15 ± 0.02 0.89 ± 0.02 1.40 ± 0.04
TT 4.66 ± 0.10 1.33(1.00) 1.42 ± 0.04 2.80 ± 0.08 1.15 ± 0.02 0.92 ± 0.02 1.32 ± 0.06
P 0.687 0.066 0.763 0.248 0.923 0.317 0.510
CC 4.64 ± 0.11 1.18(0.81) 1.46 ± 0.04 2.76 ± 0.08 1.16 ± 0.03 0.90 ± 0.02 1.37 ± 0.06
CT + TT 4.60 ± 0.06 1.21(0.79) 1.44 ± 0.02 2.70 ± 0.05 1.15 ± 0.01 0.90 ± 0.01 1.37 ± 0.03
P 0.718 0.359 0.690 0.536 0.738 0.852 0.969
IS
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GG 4.63 ± 0.17 1.32(0.99) 1.19 ± 0.06 2.73 ± 0.13 1.02 ± 0.03 0.94 ± 0.04 1.11 ± 0.09
GA 4.51 ± 0.07 1.41(0.95) 1.22 ± 0.03 2.68 ± 0.06 1.03 ± 0.02 0.90 ± 0.02 1.18 ± 0.04
AA 4.51 ± 0.07 1.27(0.91) 1.24 ± 0.03 2.67 ± 0.06 1.02 ± 0.02 0.88 ± 0.02 1.17 ± 0.04
P 0.799 0.480 0.581 0.928 0.884 0.235 0.751
GG 4.63 ± 0.17 1.32(0.99) 1.19 ± 0.06 2.73 ± 0.13 1.02 ± 0.03 0.94 ± 0.04 1.11 ± 0.09
GA + AA 4.51 ± 0.05 1.36(0.93) 1.23 ± 0.02 2.68 ± 0.04 1.02 ± 0.01 0.89 ± 0.01 1.18 ± 0.03
P 0.503 0.765 0.496 0.703 0.967 0.147 0.501
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CC 4.53 ± 0.11 1.27(1.06) 1.22 ± 0.04 2.68 ± 0.09 1.01 ± 0.02 0.90 ± 0.02 1.20 ± 0.06
CT 4.52 ± 0.07 1.39(0.93) 1.21 ± 0.02 2.68 ± 0.05 1.02 ± 0.01 0.89 ± 0.02 1.16 ± 0.04
TT 4.52 ± 0.09 1.34(0.88) 1.26 ± 0.03 2.69 ± 0.07 1.03 ± 0.02 0.89 ± 0.02 1.16 ± 0.05
P 0.997 0.324 0.372 0.992 0.844 0.906 0.823
CC 4.53 ± 0.11 1.27(1.06) 1.22 ± 0.04 2.68 ± 0.09 1.01 ± 0.02 0.90 ± 0.02 1.20 ± 0.06
CT + TT 4.52 ± 0.06 1.37(0.92) 1.23 ± 0.02 2.68 ± 0.04 1.03 ± 0.01 0.89 ± 0.01 1.16 ± 0.03
P 0.943 0.210 0.913 0.941 0.632 0.664 0.533
  1. The value of triglyceride was presented as median (interquartile range) and used nonparametric Test
  2. TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoAI apolipoprotein AI, ApoB apolipoprotein B CAD coronary artery disease, IS ischemic stroke