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Table 4 Allelic and genotypic associations of 6 SNPs with CAD risk in our case–control study

From: Associations of lipid levels susceptibility loci with coronary artery disease in Chinese population

SNP

Genotype

Frequency (n)

Allelic comparison

Additive model

Dominant model

Recessive model

  

Cases

Controls

OR (95 % CI)

P

PFDR a

OR (95 % CI)

P

PFDR a

OR (95 % CI)

P

PFDR a

OR (95 % CI)

P

PFDR a

rs1169288

AA

318

359

1.18 (1.05, 1.33)

0.006

0.030

1.25 (1.06, 1.45)

0.008

0.033

1.45 (1.13, 1.86)

0.004

0.025

1.22 (0.93, 1.61)

0.149

0.310

C vs A

AC

526

500

            
 

CC

256

210

            

rs7395662

GG

239

301

1.20 (1.07, 1.36)

0.002

0.025

1.22 (1.05, 1.43)

0.012

0.043

1.50 (1.15, 1.97)

0.003

0.025

1.18 (0.91, 1.52)

0.212

0.379

A vs G

AG

562

508

            
 

AA

299

260

            

rs1495741

AA

195

209

1.15 (1.02, 1.30)

0.024

0.075

1.16 (0.99, 1.36)

0.058

0.145

1.09 (0.82, 1.45)

0.546

0.696

1.31 (1.03, 1.66)

0.029

0.081

G vs A

AG

510

529

            
 

GG

395

331

            

rs12670798

TT

259

293

1.08 (0.96, 1.22)

0.188

0.362

1.07 (0.92, 1.25)

0.398

0.622

1.19 (0.97, 1.47)

0.098

0.223

1.13 (0.87, 1.46)

0.354

0.590

T vs C

TC

568

512

            
 

CC

270

261

            

rs9411489

CC

688

657

0.96 (0.83, 1.11)

0.621

0.739

0.98 (0.84, 1.15)

0.821

0.892

1.00 (0.83, 1.20)

0.998

0.998

0.97 (0.64, 1.49)

0.904

0.942

T vs C

TC

355

355

            
 

TT

57

57

            

rs10128711

TT

313

321

1.04 (0.92, 1.17)

0.557

0.696

1.05 (0.92, 1.21)

0.446

0.656

1.09 (0.88, 1.36)

0.483

0.671

1.05 (0.85, 1.31)

0.659

0.749

C vs T

TC

534

499

            
 

CC

253

244

            
  1. Italic values are statistically significant after FDR correction
  2. OR (95 % CI), odds ratio (95 % confidence interval)
  3. aP-value from Benjamini-Hochberg method control for false discovery rate (FDR)