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Table 4 Allelic and genotypic associations of 6 SNPs with CAD risk in our case–control study

From: Associations of lipid levels susceptibility loci with coronary artery disease in Chinese population

SNP Genotype Frequency (n) Allelic comparison Additive model Dominant model Recessive model
   Cases Controls OR (95 % CI) P PFDR a OR (95 % CI) P PFDR a OR (95 % CI) P PFDR a OR (95 % CI) P PFDR a
rs1169288 AA 318 359 1.18 (1.05, 1.33) 0.006 0.030 1.25 (1.06, 1.45) 0.008 0.033 1.45 (1.13, 1.86) 0.004 0.025 1.22 (0.93, 1.61) 0.149 0.310
C vs A AC 526 500             
  CC 256 210             
rs7395662 GG 239 301 1.20 (1.07, 1.36) 0.002 0.025 1.22 (1.05, 1.43) 0.012 0.043 1.50 (1.15, 1.97) 0.003 0.025 1.18 (0.91, 1.52) 0.212 0.379
A vs G AG 562 508             
  AA 299 260             
rs1495741 AA 195 209 1.15 (1.02, 1.30) 0.024 0.075 1.16 (0.99, 1.36) 0.058 0.145 1.09 (0.82, 1.45) 0.546 0.696 1.31 (1.03, 1.66) 0.029 0.081
G vs A AG 510 529             
  GG 395 331             
rs12670798 TT 259 293 1.08 (0.96, 1.22) 0.188 0.362 1.07 (0.92, 1.25) 0.398 0.622 1.19 (0.97, 1.47) 0.098 0.223 1.13 (0.87, 1.46) 0.354 0.590
T vs C TC 568 512             
  CC 270 261             
rs9411489 CC 688 657 0.96 (0.83, 1.11) 0.621 0.739 0.98 (0.84, 1.15) 0.821 0.892 1.00 (0.83, 1.20) 0.998 0.998 0.97 (0.64, 1.49) 0.904 0.942
T vs C TC 355 355             
  TT 57 57             
rs10128711 TT 313 321 1.04 (0.92, 1.17) 0.557 0.696 1.05 (0.92, 1.21) 0.446 0.656 1.09 (0.88, 1.36) 0.483 0.671 1.05 (0.85, 1.31) 0.659 0.749
C vs T TC 534 499             
  CC 253 244             
  1. Italic values are statistically significant after FDR correction
  2. OR (95 % CI), odds ratio (95 % confidence interval)
  3. aP-value from Benjamini-Hochberg method control for false discovery rate (FDR)