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Table 5 Associations of 6 SNPs with the vessel scores in the 1100 CAD patients

From: Associations of lipid levels susceptibility loci with coronary artery disease in Chinese population

SNP

Diseased vessel scores (%)

χ 2 test

Linear-by- linear χ 2 test

 

1

2

3

χ 2 value

P

PFDR a

χ 2 value

P

rs1169288

   

16.507

0.002

0.012

6.120

0.013

AA

126 (33.9)

95 (32.3)

97 (22.4)

     

AC

161 (43.3)

131 (44.6)

234 (53.9)

     

CC

85 (22.8)

68 (23.1)

103 (23.7)

     

rs7395662

   

5.620

0.229

0.458

0.888

0.346

GG

81 (21.8)

68 (23.1)

90 (20.7)

     

AG

190 (51.1)

160 (54.4)

212 (48.9)

     

AA

101 (27.1)

66 (22.5)

132 (30.4)

     

rs1495741

   

3.071

0.546

0.655

1.580

0.209

AA

64 (17.2)

53 (18.0)

78 (18.0)

     

AG

165 (44.4)

132 (44.9)

213 (49.1)

     

GG

143 (38.4)

109 (37.1)

143 (32.9)

     

rs12670798

   

8.320

0.081

0.243

0.005

0.944

TT

93 (25.1)

77 (26.3)

89 (20.6)

     

TC

179 (48.2)

142 (48.5)

247 (57.0)

     

CC

99 (26.7)

74 (25.2)

97 (22.4)

     

rs9411489

   

0.337

0.987

0.987

0.106

0.745

CC

230 (61.8)

186 (63.3)

272 (62.7)

     

TC

121 (32.5)

94 (31.9)

140 (32.3)

     

TT

21 (5.7)

14 (4.8)

22 (5.0)

     

rs10128711

   

3.126

0.537

0.655

2.750

0.097

TT

97 (26.0)

86 (29.2)

130 (30.0)

     

TC

181 (48.7)

139 (47.3)

214 (49.3)

     

CC

94 (25.3)

69 (23.5)

90 (20.7)

     
  1. Italic values are statistically significant after FDR correction
  2. aP-value from Benjamini-Hochberg method control for false discovery rate (FDR)