Fig. 2

Possible mechanism of action of melatonin on improving dyslipidemia and hepatic steatosis. (O⁻ = superoxide; H₂0₂ = hydrogen peroxide; OH^. = hydroxyl radicals; ROO^. = organic peroxy radicals; ¹0₂₌ singlet oxygen ; NO^. = nitric oxide; ONOO⁻ = nitric oxide; GSH-Px = glutathione peroxidase; GSH-Rd = glutathione reductase; CAT = catalase; G6PD = glucose-6-phosphate dehydrogenase; SOD = superoxide dismutase; MDA = malondialdehyde; NOS = nitric oxide synthase; SREBP-1c = sterol regulatory element-binding protein-1c; IL-1β = interleukin-1β; IL-6 = interleukin-6; TNF-α = Tumor Necrosis Factor-α; NK = Natural Killer; IL-1 = interleukin-1; ALT = Alanine transaminase; AST = Aspertate Aminotransferase; TC = total cholesterol; TG = Triglyceride; LDL-C = low density lipoprotein; HDL-C = high density lipoprotein.)