Parameter | 4w | 6w | |||||
---|---|---|---|---|---|---|---|
Normal group | NAFLD group | Normal group | Low-dose group | Middle-dose group | High-dose group | Positive control group | |
AST (U/L) | 75.17 ± 4.31 | 96.85 ± 7.63★★ | 76.29 ± 5.16 | 97.36 ± 6.82** | 93.75 ± 4.55* | 88.34 ± 6.27*# | 101.67 ± 8.36 |
ALT(U/L) | 28.16 ± 1.21 | 51.28 ± 3.26★★ | 29.25 ± 1.72 | 53.28 ± 4.41** | 49.78 ± 2.19** | 44.29 ± 2.22**# | 56.35 ± 4.16 |
TG(mmol/L) | 0.59 ± 0.09 | 1.65 ± 0.08★★ | 0.61 ± 0.04 | 1.81 ± 0.11** | 1.46 ± 0.09**# | 0.92 ± 0.03**## | 2.12 ± 0.12 |
TC(mmol/L) | 1.66 ± 0.12 | 3.14 ± 0.13★★ | 1.70 ± 0.09 | 3.82 ± 0.15** | 3.65 ± 0.17**# | 2.65 ± 0.12**## | 4.54 ± 0.24 |
LDL-C (mmol/L) | 0.54 ± 0.03 | 1.25 ± 0.08★★ | 0.56 ± 0.04 | 1.37 ± 0.08** | 1.24 ± 0.05** | 1.09 ± 0.06**# | 1.35 ± 0.09 |
HDL-C (mmol/L) | 0.96 ± 0.04 | 0.64 ± 0.04★★ | 0.98 ± 0.05 | 0.64 ± 0.03** | 0.69 ± 0.05** | 0.77 ± 0.04*# | 0.55 ± 0.03 |
GLU (mmol/L) | 4.68 ± 0.15 | 5.07 ± 0.21 | 4.56 ± 0.18 | 4.99 ± 0.87 | 5.07 ± 0.04 | 5.13 ± 18.88 | 5.41 ± 0.19 |
TBA(μmol/L) | 6.75 ± 0.05 | 10.23 ± 0.06★★ | 6.54 ± 0.06 | 11.53 ± 1.27** | 11.04 ± 0.98** | 10.24 ± 0.05**# | 12.27 ± 1.25 |
Leptin (μg/L) | 0.18 ± 0.01 | 0.32 ± 0.01★ | 0.19 ± 0.02 | 0.46 ± 0.03** | 0.34 ± 0.02*# | 0.28 ± 0.01# | 0.46 ± 0.03 |
SOD (U/mL) | 374.36 ± 17.86 | 300.4 ± 20.1★★ | 370.35 ± 19.46 | 293.4 ± 24.1** | 321.79 ± 23.16* | 348.32 ± 19.76# | 297.84 ± 23.17 |
MDA (nmol/mL) | 3.26 ± 0.21 | 4.27 ± 0.16★★ | 3.25 ± 0.75 | 4.98 ± 1.32* | 4.77 ± 0.87* | 3.84 ± 0.99## | 5.04 ± 1.27 |
GSH-Px (U/mL) | 256.21 ± 19.25 | 210.45 ± 14.2★ | 255.98 ± 20.54 | 206.88 ± 15.3** | 211.57 ± 17.45**# | 238.78 ± 14.25# | 194.21 ± 17.35 |