Skip to main content

Table 2 Effects of diet supplementation with FSC-S and FSC-SpEt on hepatic lipids and GLU in normal and experimental hypercholesterolemic (HCL) mice

From: A comparative study between Wuweizi seed and its post-ethanol extraction residue in normal and hypercholesterolemic mice

Groups Dose TC TG GLU
(%, w/w) (μmol/g) (μmol/g) (μmol/g)
Normal mice     
ND 3.94 ± 0.11 7.14 ± 0.15 132.98 ± 3.13
ND/FSC-S 9 3.21 ± 0.09** 8.14 ± 0.31** 100.86 ± 2.80**
ND/FSC-SpEt 9 3.31 ± 0.13** 5.73 ± 0.18** 138.95 ± 3.83
ND/FF 0.05 1.61 ± 0.06** 3.54 ± 0.25** 95.37 ± 3.67**
HCL mice     
ND 7.35 ± 0.08 6.82 ± 0.11 106.81 ± 3.83
HCBD 11.52 ± 0.55** 11.12 ± 0.82** 107.67 ± 2.88
HCBD/FSC-S 3 12.45 ± 0.39 13.05 ± 0.58 97.57 ± 2.35#
  9 11.90 ± 0.05 13.35 ± 0.48# 84.48 ± 1.65##
HCBD/FSC-SpEt 3 11.59 ± 0.51 10.13 ± 0.43 102.84 ± 1.67
  9 10.70 ± 0.47 9.70 ± 0.55 104.73 ± 1.67
HCBD/FF 0.05 7.02 ± 0.22## 6.34 ± 0.15## 65.67 ± 2.14##
  1. Experimental details were described in Table 1. Mice were fed with ND and HCBD without or with FSC-S, FSC-SpEt, or FF supplementation. Ten days after supplementation, hepatic TC, TG and GLU contents were determined. Values given are the means ± SEM, with n = 10. * P < 0.05, ** P < 0.01 vs ND; # P < 0.05, ## P < 0.01 vs HCBD. Statistical significant differences were determined using a one-way ANOVA followed by Dunnett’s multiple comparisons test or post-hoc analysis