Skip to main content

Table 5 Effects of FSC-S and FSC-SpEt supplementation on stomach and residual gastric content and fecal TC excretion in normal and experimental hypercholesterolemic (HCL) mice

From: A comparative study between Wuweizi seed and its post-ethanol extraction residue in normal and hypercholesterolemic mice

Groups Drug dose (%, w/w) Stomach Residual gastric content Fecal TC (μmol/g)
Weight (g) Index 1 Index 2 Weight (g) Index 1 Index 2
Normal mice         
ND 0.34 ± 0.02 1.18 ± 0.06 1.26 ± 0.06 0.55 ± 0.06 1.92 ± 0.20 2.05 ± 0.21 5.91 ± 0.22
ND/FSC-S 9 0.25 ± 0.02** 1.25 ± 0.06 1.38 ± 0.07 0.73 ± 0.06* 3.59 ± 0.20** 3.97 ± 0.23** 5.21 ± 0.57
ND/FSC-SpEt 9 0.32 ± 0.01 1.12 ± 0.03 1.20 ± 0.03 0.45 ± 0.05 1.59 ± 0.19 1.70 ± 0.20 4.82 ± 0.29**
ND/FF 0.05 0.28 ± 0.02* 1.02 ± 0.05* 1.31 ± 0.06 0.42 ± 0.03 1.53 ± 0.10 1.70 ± 0.11 6.72 ± 0.40
HCL mice         
ND 0.31 ± 0.01 1.06 ± 0.03 1.13 ± 0.03 0.61 ± 0.09 2.06 ± 0.26 2.20 ± 0.28 5.24 ± 0.47
HCBD 0.30 ± 0.01 1.05 ± 0.03 1.12 ± 0.03 0.53 ± 0.06 1.82 ± 0.20 1.96 ± 0.22 23.18 ± 1.00**
HCBD/FSC-S 3 0.29 ± 0.01 0.99 ± 0.04 1.08 ± 0.04 0.49 ± 0.09 1.70 ± 0.32 1.88 ± 0.37 23.72 ± 0.80
  9 0.28 ± 0.01 1.12 ± 0.04 1.26 ± 0.04# 0.66 ± 0.08 2.57 ± 0.27# 2.91 ± 0.31# 20.86 ± 1.06
HCBD/FSC-SpEt 3 0.31 ± 0.02 1.08 ± 0.06 1.16 ± 0.06 0.36 ± 0.02# 1.27 ± 0.07# 1.37 ± 0.08# 25.43 ± 1.72
  9 0.30 ± 0.01 1.07 ± 0.04 1.15 ± 0.04 0.41 ± 0.04# 1.41 ± 0.12 1.53 ± 0.13 24.87 ± 0.96
HCBD/FF 0.05 0.31 ± 0.01 1.10 ± 0.04 1.25 ± 0.04# 0.37 ± 0.04# 1.29 ± 0.11# 1.47 ± 0.12 27.84 ± 1.19##
  1. Experimental details were described in Table 1 and 3. Mice were fed with ND and HCBD without or with FSC-S, FSC-SpEt, or FF supplementation. Ten days after supplementation, stomach weight and the values of gastric content and fecal TC were measured. Stomach and residual gastric content index was estimated from the ratio of their weight to body weight × 100 (index 1) or the ratio of their weight to body weight – liver weight × 100 (index 2). Values given are the means ± SEM, with n = 10. * P < 0.05, ** P < 0.01 vs ND; # P < 0.05, ## P < 0.01 vs HCBD. Statistical significant differences were determined using a one-way ANOVA followed by Dunnett’s multiple comparisons test or post-hoc analysis