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Table 1 Fatty acid profile of regular chow, FO, CO and tumor tissue

From: Fish oil administration mediates apoptosis of Walker 256 tumor cells by modulation of p53, Bcl-2, caspase-7 and caspase-3 protein expression

Fatty acids (g/100 g total fatty acids) Regular chow Fish oil Coconut fat Tumor tissue
     W WFO WCO
Lauric acid (12:0) 1.3 ± 0.3 4.8 ± 0.1 45.3 ± 3.1 4.6 ± 1.4 2.3 ± 0.4 5.4 ± 1.8
Miristic acid (14:0) - 9.9 ± 0.1 17.0 ± 1.9 1.8 ± 1.8 2.5 ± 1.4 2.2 ± 1.3
Palmitic acid (16:0) 13.7 ± 0.9 16.7 ± 0.2 25.0 ± 2.8 19.2 ± 0.2 16.9 ± 0.2 15.3 ± 0.3
Stearic acid (18:0) 2.4 ± 0.3 1.9 ± 0.3 1.9 ± 0.2 12.6 ± 0.4 5.7 ± 1.2 8.5 ± 1.1
Oleic acid (18:1n-9) 20.0 ± 0.1 10.6 ± 0.1 7.9 ± 0.2 18.9 ± 0.7 22.6 ± 0.2 22.6 ± 0.5
Linoleic acid (18:2n-6) 56.0 ± 0.8 11.6 ± 0.1 2.0 ± 1.2 20.5 ± 0.5 35.4 ± 0.1 33.7 ± 1.1
α -Linolenic acid (18:3n-3) 6.0 ± 0.6 - 0.9 ± 0.1 0.5 ± 0.1 2.0 ± 0.2 1.6 ± 1.5
Arachidonic acid (20:4n-6) 0.3 ± 0.2 0.7 ± 0.1 - 19.0 ± 0.4 6.5 ± 0.3 8.5 ± 0.6
Eicosapentaenoic acid (20:5n-3) 0.2 ± 0.1 23.9 ± 0.6 - 0.3 ± 0.3 2.0 ± 0.7* 0.4 ± 0.3
Docosahexaenoic acid (22:6n-3) - 19.8 ± 0.8 - 2.5 ± 1.1 4.1 ± 1.8* 1.8 ± 1.7
n-6 / n-3 PUFA ratio 9.0 1.4 8.4 12.0 5.2 11.0
  1. Fatty acid composition of regular chow, fish oil (FO), coconut fat (CO) and tumor tissue by high performance liquid chromatographer. Data are mean ± SEM (n = 9) of Walker 256 tumor-bearing rats (W), Walker 256 tumor-bearing rats supplemented with fish oil (WFO) and coconut fat (WCO) * p < 0.05 vs. W and WCO group