Table 2 Hardy-Weinberg equilibrium test of four genotypes
Genotype | Observed frequency | Expected frequency | χ 2 | P |
|---|---|---|---|---|
MTHFR C677T | ||||
 CC | 108 (25.4) | 107.3 (25.2) | 0.021 | 0.885 |
 CT | 211 (49.6) | 212.5 (50.0) | ||
 TT | 106 (24.9) | 105.3 (24.8) | ||
MTHFR A1298C | ||||
 AA | 299 (70.4) | 296.5 (69.8) | 0.759 | 0.384 |
 AC | 112 (26.4) | 116.9 (27.5) | ||
 CC | 14 (3.3) | 11.5 (2.7) | ||
MTR A2756G | ||||
 AA | 348 (81.9) | 347.9 (81.9) | 0.006 | 0.937 |
 AG | 73 (17.2) | 73.3 (17.2) | ||
 GG | 4 (0.9) | 3.9 (0.9) | ||
MTRR A66G | ||||
 AA | 137 (32.2) | 141.2 (33.2) | 0.708 | 0.400 |
 AG | 216 (50.8) | 207.5 (48.8) | ||
 GG | 72 (16.9) | 76.2 (17.9) | ||