Joint associations of folate, homocysteine and MTHFR, MTR and MTRR gene polymorphisms with dyslipidemia in a Chinese hypertensive population: a cross-sectional study

Table 4 Effect of low folate on serum lipids status

Folate status^a	TC		OR (95 % CI)	P^b	TAG		OR (95 % CI)	P^b
Folate status^a	>5.18	≤5.18	OR (95 % CI)	P^b	>1.70	≤1.70	OR (95 % CI)	P^b
High FA, %	71.5	72.3	Ref.		63.9	76.2	Ref.
Low FA, %	28.5	27.7	0.87 (0.54-1.40)	0.569	36.1	23.8	2.02 (1.25-3.25)	0.004
	HDL-C		OR (95 % CI)	P^b	LDL-C		OR (95 % CI)	P^b
	<1.04	≥1.04	OR (95 % CI)	P^b	>3.37	≤3.37	OR (95 % CI)	P^b
High FA, %	61.7	74.9	Ref.		71.3	72.3	Ref.
Low FA, %	38.3	25.1	1.88 (1.07-3.28)	0.027	28.7	27.7	0.91 (0.56-1.48)	0.698

TC total cholesterol, TAG triacylglycerols, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
^aHigh FA: serum folate level ≥ 10 nmol/L, Low FA: serum folate level < 10 nmol/L
^bAdjusted for sex, age, clinical centers, height and weight

ISSN: 1476-511X