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Table 4 Effect of low folate on serum lipids status

From: Joint associations of folate, homocysteine and MTHFR, MTR and MTRR gene polymorphisms with dyslipidemia in a Chinese hypertensive population: a cross-sectional study

Folate statusa TC OR (95 % CI) Pb TAG OR (95 % CI) Pb
>5.18 ≤5.18 >1.70 ≤1.70
 High FA, % 71.5 72.3 Ref.   63.9 76.2 Ref.  
 Low FA, % 28.5 27.7 0.87 (0.54-1.40) 0.569 36.1 23.8 2.02 (1.25-3.25) 0.004
  HDL-C OR (95 % CI) Pb LDL-C OR (95 % CI) Pb
  <1.04 ≥1.04 >3.37 ≤3.37
 High FA, % 61.7 74.9 Ref.   71.3 72.3 Ref.  
 Low FA, % 38.3 25.1 1.88 (1.07-3.28) 0.027 28.7 27.7 0.91 (0.56-1.48) 0.698
  1. TC total cholesterol, TAG triacylglycerols, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
  2. aHigh FA: serum folate level ≥ 10 nmol/L, Low FA: serum folate level < 10 nmol/L
  3. bAdjusted for sex, age, clinical centers, height and weight