Table 5 Associations of genotypes and serum lipid profiles

MTHFR C677T

 CC

5.01 ± 1.42

Reference

1.75 ± 1.06

Reference

 CT

4.94 ± 0.98

-0.05 (0.13)

0.337

1.75 ± 1.19

-0.01 (0.13)

0.799

 TT

5.12 ± 1.00

0.02 (0.08)

0.811

1.69 ± 1.49

-0.03 (0.08)

0.701

MTHFR A1298C

 AA

4.97 ± 0.98

Reference

1.69 ± 1.15

Reference

 AC

5.10 ± 1.45

0.05 (0.12)

0.263

1.89 ± 1.48

0.06 (0.13)

0.231

 CC

4.94 ± 0.83

0.01 (0.12)

0.846

1.56 ± 0.94

-0.03 (0.15)

0.633

MTR A2756G

 AA

5.02 ± 1.11

Reference

1.76 ± 1.30

Reference

 AG

4.92 ± 1.09

-0.00 (0.14)

0.966

1.62 ± 0.93

-0.02 (0.15)

0.698

 GG

5.18 ± 2.23

0.02 (0.28)

0.714

1.73 ± 0.40

-0.02 (0.31)

0.703

MTRR A66G

 AA

4.82 ± 0.99

Reference

1.71 ± 1.25

Reference

 AG

5.03 ± 0.95

0.09 (0.10)

0.091

1.77 ± 1.30

-0.01 (0.13)

0.853

 GG

5.27 ± 1.64

0.14 (0.09)

0.054

1.70 ± 1.03

-0.02 (0.08)

0.757

Genotype

Mean ± SD

β (SE)^a

P^b

Mean ± SD

β (SE)^a

P^b

MTHFR C677T

 CC

1.33 ± 0.36

Reference

2.87 ± 0.83

Reference

 CT

1.28 ± 0.35

-0.08 (0.04)

0.111

2.91 ± 0.80

0.01 (0.10)

0.801

 TT

1.34 ± 0.39

-0.01 (0.02)

0.904

2.97 ± 0.74

0.04 (0.05)

0.550

MTHFR A1298C

 AA

1.30 ± 0.36

Reference

2.93 ± 0.77

Reference

 AC

1.31 ± 0.36

0.02 (0.04)

0.689

2.89 ± 0.84

-0.02 (0.09)

0.707

 CC

1.39 ± 0.48

0.08 (0.05)

0.129

2.92 ± 0.82

0.00 (0.11)

0.993

MTR A2756G

 AA

1.31 ± 0.37

Reference

2.91 ± 0.78

Reference

 AG

1.28 ± 0.33

-0.02 (0.04)

0.658

2.91 ± 0.84

0.01 (0.10)

0.784

 GG

1.33 ± 0.42

0.04 (0.09)

0.456

3.39 ± 0.85

0.06 (0.20)

0.288

MTRR A66G

 AA

1.27 ± 0.37

Reference

2.85 ± 0.79

Reference

 AG

1.32 ± 0.35

0.06 (0.04)

0.223

2.94 ± 0.80

0.06 (0.09)

0.303

 GG

1.36 ± 0.37

0.07 (0.03)

0.274

2.98 ± 0.77

0.06 (0.06)

0.369