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Table 2 Results from survival models that evaluated the association of blood lipids and lipoproteins on 10-year all-cause mortality and CVD incidence, among the ATTICA study participants (n = 2,583)

From: Hierarchical modelling of blood lipids’ profile and 10-year (2002–2012) all cause mortality and incidence of cardiovascular disease: the ATTICA study

  All-cause mortality CVD incidence
Independent predictor RR 95 % CI RR 95 % CI
Model 1: Total cholesterol (per 1 mg/dL*) 1.006 1.000,1.013 1.003 0.999,1.007
Model 2: HDL cholesterol (per 1 mg/dL) 0.988 0.962,1.015 0.983 0.967,1.000
Model 3: LDL cholesterol (per 1 mg/dL) 1.004 0.996,1.011 1.002 0.998.1.007
Model 4: non-HDL cholesterol (per 1 mg/dL) 1.006 1.000,1.013 1.005 1.001,1.009
Model 5: Triglycerides (per 1 mg/dL) 1.002 1.000,1.004 1.002 1.001,1.003
Model 5: Lipoprotein-a (per 1 mg/dL) 1.004 0.994,1.015 1.003 0.997,1.010
Model 6: Apolipoprotein-A1 (per 1 mg/dL) 0.991 0.978,1.004 0.992 0.985,1.000
Model 7: Apolipoprotein-B (per 1 mg/dL) 1.004 0.997,1.012 1.002 0.998,1.007
Model 8: Total/HDL-cholesterol ratio (per 1 unit) 1.169 0.978,1.387 1.216 1.092,1.354
Model 9: Apolipoprotein-B/-A1 ratio (per 1 unit) 1.560 0.837,2.910 1.389 0.921,2.094
Model 10: Triglycerides/ HDL-cholesterol ratio (per 1 unit) 1.038 1.001,1.077 1.055 1.031,1.078
  1. All models were adjusted for age, sex, BMI, smoking habits, physical activity status, MedDietScore and history and pharmaceutical management of dyslipidemias, hypertension and diabetes, and family history of CVD at baseline examination. Results are presented as Relative Risk (RR) and 95 % Confidence Interval (CI)
  2. *1 mg/dL corresponds to 0.0259 mmol/L for Total cholesterol, HDL cholesterol, LDL cholesterol, non-HDL cholesterol and to 0.0115 mmol/L for Triglycerides