The association of cholesterol absorption gene Numb polymorphism with Coronary Artery Disease among Han Chinese and Uighur Chinese in Xinjiang, China

Mayila Abudoukelimu; Zhen-Yan Fu; Ailifeire Maimaiti; Yi-Tong Ma; Minawaer Abudu; Qing Zhu; Dilare Adi; Yi-Ning Yang; Xiao-Mei Li; Xiang Xie; Fen Liu; Bang-Dang Chen

doi:10.1186/s12944-015-0102-6

Table 1 Characteristics of subjects (Han Chinese)

From: The association of cholesterol absorption gene Numb polymorphism with Coronary Artery Disease among Han Chinese and Uighur Chinese in Xinjiang, China

	Total			Male			Female
	CAD patients	Control subjects	P Value	CAD patients	Control subjects	P Value	CAD patients	Control subjects	P Value
Number(n)	384	433		270	220		114	213
Age(years)	59.65 ± 0.501	58.91 ± 0.470	0.284	58.13 ± 0.563	58.86 ± 0.618	0.427	58.25 ± 0.714	58.95 ± 0.589	0.335
BMI(kg/m²)	26.03 ± 0.167	25.22 ± 0.151	0.000^*	26.34 ± 0.194	25.33 ± 0.212	0.010^*	26.29 ± 0.315	25.12 ± 0.232	0.000^*
Glu(mmol/L)	6.58 ± 0.162	5.48 ± 0.111	0.000^*	6.22 ± 0.211	6.07 ± 0.196	0.000^*	6.18 ± 0.200	5.77 ± 0.146	0.000^*
BUN(mmol/L)	5.65 ± 0.102	5.19 ± 0.091	0.001^*	5.71 ± 0.227	5.27 ± 0.121	0.087	5.16 ± 0.142	5.51 ± 0.145	0.129
TG(mmol/L)	2.43 ± 0.084	1.99 ± 0.067	0.000^*	2.46 ± 0.105	2.02 ± 0.090	0.003^*	2.35 ± 0.134	1.96 ± 0.107	0.027^*
TC(mmol/L)	4.55 ± 0.067	4.23 ± 0.064	0.001^*	4.53 ± 0.083	4.28 ± 0.090	0.004^*	4.59 ± 0.111	4.19 ± 0.088	0.009^*
LDL-C(mmol/L)	2.73 ± 0.045	2.56 ± 0.038	0.009^*	2.75 ± 0.057	2.60 ± 0.061	0.030^*	2.59 ± 0.074	2.52 ± 0.047	0.008^*
HDL-C(mmol/L)	1.14 ± 0.031	1.12 ± 0.025	0.636	1.16 ± 0.042	1.12 ± 0.051	0.577	1.11 ± 0.031	1.12 ± 0.028	0.726
VLDL (mmol/L)	0.49 ± 0.017	0.40 ± 0.014	0.000^*	0.49 ± 0.022	0.40 ± 0.019	0.003^*	0.47 ± 0.028	0.39 ± 0.028	0.027^*
DM(%)	143(66.6 %)	72(33.4 %)	0.000^*	163(74.1 %)	36(25.9 %)	0.000^*	40(52.6 %)	36(47.4 %)	0.000^*
EH(%)	221(52.2 %)	201(47.8 %)	0.030^*	145(60.4 %)	95(39.6 %)	0.024^*	53(35.3 %)	47(64.7 %)	0.991
Hyperlipidemia(%)	136(54.8 %)	112(45.2 %)	0.000^*	165(53.9 %)	141(46.1 %)	0.012^*	79(37.3 %)	133(62.7 %)	0.040^*
Smoking(%)	287(59.8 %)	193(40.2 %)	0.000^*	170(57.2 %)	127(42.8 %)	0.000^*	120(61.9 %)	74(38.1 %)	0.000^*

BMI body mass index, Glu glucose, BUN blood urea nitrogen, TG triglyceride, TC total cholesterol, LDL-C low density lipoprotein-cholesterol, HDL-C high density lipoprotein-cholesterol, VLDL very low density lipoprotein, DM diabetes mellitus, EH essential hypertension. Continuous variable were expressed as mean ± standard error of mean (SEM). P value of continuous variables was calculated by independent T-test. The P value of categorical variable was calculated by Fisher’s exact test. ^* P < 0.05

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