The association of cholesterol absorption gene Numb polymorphism with Coronary Artery Disease among Han Chinese and Uighur Chinese in Xinjiang, China

Mayila Abudoukelimu; Zhen-Yan Fu; Ailifeire Maimaiti; Yi-Tong Ma; Minawaer Abudu; Qing Zhu; Dilare Adi; Yi-Ning Yang; Xiao-Mei Li; Xiang Xie; Fen Liu; Bang-Dang Chen

doi:10.1186/s12944-015-0102-6

Table 2 Characteristics of subjects (Uighur Chinese)

From: The association of cholesterol absorption gene Numb polymorphism with Coronary Artery Disease among Han Chinese and Uighur Chinese in Xinjiang, China

	Total			Male			Female
	CAD patients	Control subjects	P Value	CAD patients	Control subjects	P Value	CAD patients	Control subjects	P Value
Number(n)	506	351		369	213		137	138
Age(years)	54.44 ± 0.407	53.37 ± 0.508	0.120	53.94 ± 0.502	53.17 ± 0.617	0.336	53.52 ± 0.710	53.21 ± 0.770	0.220
BMI(kg/m²)	27.99 ± 0.183	26.96 ± 0.273	0.001^*	27.39 ± 0.189	25.39 ± 0.321	0.000^*	26.63 ± 0.413	25.38 ± 0.406	0.000^*
Glu(mmol/L)	6.81 ± 0.108	6.35 ± 0.147	0.001^*	6.73 ± 0.124	6.45 ± 0.159	0.000^*	6.89 ± 0.218	6.16 ± 0.206	0.004^*
BUN(mmol/L)	5.68 ± 0.137	6.28 ± 0.281	0.030^*	5.76 ± 0.171	6.36 ± 0.242	0.030^*	5.48 ± 0.185	6.14 ± 0.339	0.100
TG(mmol/L)	2.47 ± 0.060	2.19 ± 0.093	0.009^*	2.46 ± 0.097	2.43 ± 0.080	0.000^*	2.49 ± 0.133	1.85 ± 0.094	0.000^*
TC(mmol/L)	4.57 ± 0.101	3.82 ± 0.088	0.000^*	4.61 ± 0.111	3.84 ± 0.110	0.109	4.51 ± 0.191	3.78 ± 0.126	0.003^*
LDL-C(mmol/L)	2.77 ± 0.043	2.62 ± 0.050	0.010^*	2.81 ± 0.048	2.70 ± 0.059	0.000^*	2.69 ± 0.076	2.50 ± 0.071	0.040^*
HDL-C(mmol/L)	0.92 ± 0.019	1.22 ± 0.062	0.001^*	0.91 ± 0.021	1.24 ± 0.045	0.000^*	0.94 ± 0.033	1.20 ± 0.043	0.010^*
VLDL (mmol/L)	0.49 ± 0.012	0.44 ± 0.019	0.009^*	0.49 ± 0.012	0.48 ± 0.027	0.000^*	0.50 ± 0.027	0.37 ± 0.020	0.000^*
DM(%)	174(64.2 %)	97(35.8 %)	0.030^*	119(65.0 %)	64(35.0 %)	0.000^*	55(62.5 %)	33(37.5 %)	0.000^*
EH(%)	250(54.1 %)	212(45.9 %)	0.002^*	162(55.7 %)	129(44.3 %)	0.000^*	88(51.5 %)	83(48.5 %)	0.535
Hyperlipidemia(%)	262(67.9 %)	212(45.9 %)	0.000^*	187(68.8 %)	85(35.0 %)	0.000^*	75(65.8 %)	39(34.2 %)	0.000^*
Smoking(%)	385(66.7 %)	192(33.2 %)	0.000^*	309(68.2 %)	144(31.8 %)	0.000^*	76(61.3 %)	48(38.7 %)	0.001^*

BMI body mass index, Glu glucose, BUN blood urea nitrogen, TG triglyceride, TC total cholesterol, LDL-C low density lipoprotein-cholesterol, HDL-C high density lipoprotein-cholesterol, VLDL very low density lipoprotein, DM diabetes mellitus, EH essential hypertension. Continuous variable were expressed as mean ± standard error of mean (SEM). P value of continuous variables was calculated by independent T-test. The P value of categorical variable was calculated by Fisher’s exact test. ^* P < 0.05

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