| | | |
Total
|
Male
|
Female
|
---|
| | | |
CAD n (%)
|
Control n (%)
|
P value
|
CAD n (%)
|
Control n (%)
|
P value
|
CAD n (%)
|
Control n (%)
|
P value
|
---|
rs12435797
|
Genotype
| |
T/T
|
173(45.6)
|
185(43.6)
|
0.378
|
125(47.2)
|
94(43.5)
|
0.436
|
48(42.1)
|
91(43.8)
|
0.924
|
(SNP1)
| | |
G/G
|
38(10.1)
|
56(13.2)
| |
22(8.3)
|
25(11.6)
| |
16(14.0)
|
31(14.9)
| |
|
G/T
|
168(44.3)
|
183(43.2)
| |
118(44.5)
|
97(44.9)
| |
50(43.9)
|
86(41.3)
| |
| |
Dominant model
|
TT
|
173(45.6)
|
185(43.6)
|
0.570
|
125(47.2)
|
94(43.5)
|
0.462
|
48(42.1)
|
91(43.8)
|
0.815
|
| | |
GT + GG
|
206(54.4)
|
239(56.4)
| |
140(52.8)
|
122(56.5)
| |
66(57.9)
|
117(56.2)
| |
| |
Recessive model
|
GG
|
38(10.1)
|
56(13.2)
|
0.187
|
22(8.3)
|
25(11.6)
|
0.280
|
16(14.0)
|
31(14.9)
|
0.871
|
| | |
GT + TT
|
341(89.9)
|
368(86.8)
| |
243(91.7)
|
191(88.4)
| |
98(86.0)
|
177(85.1)
| |
| |
Additive model
|
GT
|
168(44.3)
|
183(43.20)
|
0.776
|
118(44.5)
|
97(44.9)
|
1
|
50(43.9)
|
86(41.3)
|
0.724
|
| | |
TT + GG
|
211(55.7)
|
241(56.80)
| |
147(55.5)
|
119(55.1)
| |
64(56.1)
|
122(58.7)
| |
|
Allele
| |
T
|
514(67.75)
|
553(65.20)
|
0.290
|
368(69.45)
|
285(65.95)
|
0.267
|
146(64.05)
|
268(64.45)
|
0.932
|
| | |
G
|
244(32.25)
|
295(34.80)
| |
162(30.55)
|
147(34.05)
| |
82(35.95)
|
148(35.55)
| |
rs2108552
|
Genotype
| |
C/C
|
112(29.2)
|
88(20.5)
|
0.013*
|
79(29.3)
|
36(16.4)
|
0.003*
|
33(28.9)
|
52(24.8)
|
0.724
|
(SNP2)
| | |
G/G
|
85(22.1)
|
116(27.1)
| |
58(21.5)
|
62(28.3)
| |
27(23.7)
|
54(25.7)
| |
| | |
C/G
|
187(48.7)
|
225(52.4)
| |
133(49.2)
|
121(55.3)
| |
54(47.4)
|
104(49.5)
| |
| |
Dominant model
|
CC
|
112(29.2)
|
88(20.5)
|
0.004*
|
79(29.3)
|
36(16.4)
|
0.001*
|
33(28.9)
|
52(24.8)
|
0.430
|
| | |
CG + GG
|
272(70.8)
|
341(79.5)
| |
191(70.7)
|
183(83.6)
| |
81(71.1)
|
158(75.2)
| |
| |
Recessive model
|
GG
|
85(22.1)
|
116(27.1)
|
0.122
|
58(21.5)
|
62(28.3)
|
0.091
|
27(23.7)
|
54(25.7)
|
0.788
|
| | |
CG + CC
|
299(77.9)
|
313(72.9)
| |
212(78.5)
|
157(71.7)
| |
87(76.3)
|
156(74.3)
| |
| |
Additive model
|
CG
|
187(48.7)
|
225(52.4)
|
0.293
|
133(49.2)
|
121(55.3)
|
0.203
|
54(47.4)
|
104(49.5)
|
0.728
|
| | |
CC + GG
|
197(51.3)
|
204(47.6)
| |
137(50.7)
|
98(44.7)
| |
60(52.6)
|
106(50.5)
| |
|
Allele
| |
C
|
411(53.55)
|
401(46.7)
|
0.007*
|
291(53.9)
|
193(44.05)
|
0.003*
|
120(52.6)
|
208(49.55)
|
0.460
|
| | |
G
|
357(46.45)
|
457(53.3)
| |
249(46.1)
|
245(55.95)
| |
108(47.4)
|
212(50.45)
| |
rs1019075
|
Genotype
| |
C/C
|
21(5.5)
|
24(5.6)
|
0.041*
|
12(4.5)
|
9(4.1)
|
0.060
|
9(7.9)
|
15(7.2)
|
0.351
|
(SNP3)
| | |
T/T
|
257(67.3)
|
252(59.0)
| |
179(66.8)
|
124(56.9)
| |
78(68.4)
|
128(61.2)
| |
| | |
C/T
|
104(27.2)
|
151(35.4)
| |
77(28.7)
|
83(39.0)
| |
27(23.7)
|
66(31.6)
| |
| |
Dominant model
|
CC
|
21(5.5)
|
24(5.6)
|
1
|
12(4.5)
|
9(4.1)
|
1
|
9(7.9)
|
15(7.2)
|
0.827
|
| | |
CT + TT
|
361(94.5)
|
403(94.4)
| |
256(95.5)
|
209(95.9)
| |
105(92.1)
|
194(92.8)
| |
| |
Recessive model
|
TT
|
257(67.3)
|
252(59.0)
|
0.016*
|
179(66.8)
|
124(56.9)
|
0.030*
|
78(68.4)
|
128(61.2)
|
0.226
|
| | |
CT + CC
|
125(32.7)
|
175(41.0)
| |
89(33.2)
|
94(43.1)
| |
36(31.6)
|
81(38.8)
| |
| |
Additive model
|
CT
|
104(27.2)
|
151(35.4)
|
0.015*
|
77(28.7)
|
83(39.0)
|
0.020*
|
27(23.7)
|
66(31.6)
|
0.158
|
| | |
CC + TT
|
278(72.9)
|
276(64.6)
| |
191(71.3)
|
133(61.0)
| |
87(76.3)
|
143(68.4)
| |
|
Allele
| |
C
|
146(19.1)
|
199(23.3)
|
0.045*
|
101(18.85)
|
101(23.6)
|
0.081*
|
45(19.75)
|
96(23.0)
|
0.371
|
| | |
T
|
618(80.9)
|
655(76.7)
| |
435(81.15)
|
341(76.4)
| |
183(80.25)
|
322(77.0)
| |
rs17781919
|
Genotype
| |
C/C
|
384(100.0)
|
429(99.89)
|
1
|
270(100.0)
|
220(100.0)
|
1
|
114(100.0)
|
209(99.5)
|
1
|
(SNP4)
| | |
C/T
|
0(0.0)
|
1(0.2)
| |
0(0.0)
|
0(0.0)
| |
0(0.0)
|
1(0.5)
| |
|
Allele
| |
C
|
768(100.0)
|
859(99.9)
|
1
|
540(100.0)
|
440(100.0)
|
1
|
228(100.0)
|
419(99.8)
|
1
|
| | |
T
|
0(0.0)
|
1(0.1)
| |
0(0.0)
|
0(0.0)
| |
0(0.0)
|
1(0.2)
| |
-
CAD coronary artery disease. The P value of genotype was calculated by Fisher’s exact test. *
P <0.05