Table 7 Haplotype analysis in patients with CAD and control subjects (Uighur Chinese)
Total(n = 857) | Male(n = 582) | Female(n = 275) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case(freq) | Control(freq) | χ2 | P value | Odds ratio(95 % CI) | Case(freq) | Control(freq) | χ2 | P value | Odds ratio(95 % CI) | Case(freq) | Control(freq) | χ2 | P value | Odds ratio(95 % CI) | |||
1 | 0100 | G G C C | 305.11(0.303) | 238.23(0.336) | 2.284 | 0.131 | 0.853(0.693–1.049) | 224.57(0.307) | 133.44(0.342) | 1.548 | 0.214 | 0.846(0.650–1.101) | 80.43(0.294) | 105.09(0.330) | 1.082 | 0.298 | 0.830(0.584–1.179) |
2 | 0110 | G G T C | 218.04(0.217) | 148.10(0.209) | 0.116 | 0.734 | 1.042(0.823–1.319) | 154.87(0.212) | 80.23(0.206) | 0.045 | 0.833 | 1.033(0.762–1.400) | 63.54(0.232) | 67.89(0.213) | 0.235 | 0.628 | 1.101(0.746–1.625) |
3 | 1010 | T C T C | 333.07(0.331) | 215.98(0.305) | 1.021 | 0.273 | 1.123(0.912–1.383) | 245.28(0.335) | 118.66(0.304) | 1.063 | 0.302 | 1.150(0.881–1.501) | 87.67(0.320) | 96.81(0.304) | 0.115 | 0.735 | 1.062(0.749–1.508) |
4 | 1100 | T G C C | 39.770.040) | 21.50(0.030) | 0.987 | 0.321 | 1.310(0.768–2.234) | 25.32(0.035) | 11.14(0.029) | 0.287 | 0.592 | 1.216(0.594–2.487) | 14.73(0.054) | 10.38(0.033) | 1.559 | 0.212 | 1.669(0.741–3.758) |
5 | 1110 | T G T C | 88.09(0.088) | 66.38(0.094) | 0.215 | 0.643 | 0.924(0.661–1.291) | 64.24(0.088) | 36.19(0.093) | 0.087 | 0.769 | 0.938(0.611–1.439) | 23.46(0.086) | 30.34(0.095) | 0.199 | 0.656 | 0.879(0.500–1.548) |