Skip to main content

Table 2 Genotypic and allele frequencies between groups

From: Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects

Gene/polymorphisms Genotype Cases Controls P
n (%) n = 100 n = 100
LEPR
rs1137101
A/A 63 (31.5) 33 (33) 30 (30)  
A/G 96 (48) 46 (46) 50 (50) 0.84c
G/G 41 (20.5) 21 (21) 20 (20)  
Allele
A 222 (0.56) 112 (0.56) 110 (0.55) 0.84b
G 178 (0.44) 88 (0.44) 90 (0.45)  
rs8179183
G/G 137 (68.5) 65 (65) 72 (72)  
G/C 59 (29.5) 31 (31) 28 (28) 0.10a
C/C 4 (2) 4 (4) 0 (0)  
Allele
G 333 (0.83) 161 (0.80) 172 (0.86) 0.14b
C 67 (0.17) 39 (0.20) 28 (0.14)  
APOA5
rs662799
T/T 139 (69.5) 70 (70) 69 (69)  
T/C 59 (29.5) 30 (30) 29 (29) 0.60a
C/C 2 (1) 0 (0) 2 (2)  
Allele
T 337 (0.84) 170 (0.85) 167 (0.84) 0.68b
C 63 (0.16) 30 (0.15) 33 (0.16)  
rs3135506
C/C 11 (5.5) 4 (4) 7 (7)  
C/G 72 (36) 39 (39) 33 (33) 0.53a
G/G 117 (58.5) 57 (57) 60 (60)  
Allele
C 94 (0.24) 47 (0.24) 47 (0.24) 1.0b
G 306 (0.76) 153 (0.76) 153 (0.76)  
APOA2
rs5082
T/T 143 (71.5) 74 (74) 69 (69) 0.56a
T/C 54 (27) 24 (24) 30 (30)  
C/C 3 (1.5) 2 (2) 1 (1)  
Allele
T 340 (0.85) 172 (0.86) 168 (0.84) 0.57b
C 60 (0.15) 28 (0.14) 32 (0.16)  
rs3813627     
G/G 200 (100) 100 100  
G/T - - - -
T/T - - -  
Allele
G 400 (1.0) 200 (1.0) 200 (1.0) -
T - - -  
  1. The genotypes analyzed in the population were in Hardy Weinberg Equilibrium
  2. aFisher’s exact test
  3. bχ2 test