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Table 2 Genotypic and allele frequencies between groups

From: Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects

Gene/polymorphisms

Genotype

Cases

Controls

P

n (%)

n = 100

n = 100

LEPR

rs1137101

A/A

63 (31.5)

33 (33)

30 (30)

 

A/G

96 (48)

46 (46)

50 (50)

0.84c

G/G

41 (20.5)

21 (21)

20 (20)

 

Allele

A

222 (0.56)

112 (0.56)

110 (0.55)

0.84b

G

178 (0.44)

88 (0.44)

90 (0.45)

 

rs8179183

G/G

137 (68.5)

65 (65)

72 (72)

 

G/C

59 (29.5)

31 (31)

28 (28)

0.10a

C/C

4 (2)

4 (4)

0 (0)

 

Allele

G

333 (0.83)

161 (0.80)

172 (0.86)

0.14b

C

67 (0.17)

39 (0.20)

28 (0.14)

 

APOA5

rs662799

T/T

139 (69.5)

70 (70)

69 (69)

 

T/C

59 (29.5)

30 (30)

29 (29)

0.60a

C/C

2 (1)

0 (0)

2 (2)

 

Allele

T

337 (0.84)

170 (0.85)

167 (0.84)

0.68b

C

63 (0.16)

30 (0.15)

33 (0.16)

 

rs3135506

C/C

11 (5.5)

4 (4)

7 (7)

 

C/G

72 (36)

39 (39)

33 (33)

0.53a

G/G

117 (58.5)

57 (57)

60 (60)

 

Allele

C

94 (0.24)

47 (0.24)

47 (0.24)

1.0b

G

306 (0.76)

153 (0.76)

153 (0.76)

 

APOA2

rs5082

T/T

143 (71.5)

74 (74)

69 (69)

0.56a

T/C

54 (27)

24 (24)

30 (30)

 

C/C

3 (1.5)

2 (2)

1 (1)

 

Allele

T

340 (0.85)

172 (0.86)

168 (0.84)

0.57b

C

60 (0.15)

28 (0.14)

32 (0.16)

 

rs3813627

    

G/G

200 (100)

100

100

 

G/T

-

-

-

-

T/T

-

-

-

 

Allele

G

400 (1.0)

200 (1.0)

200 (1.0)

-

T

-

-

-

 
  1. The genotypes analyzed in the population were in Hardy Weinberg Equilibrium
  2. aFisher’s exact test
  3. bχ2 test