Table 3 Clinical, biochemical and nutritional variables according to polymorphisms in APOA5, LEPR and APOA2 genes
Variables | Polymorphism −1131 T/C in the gene APOA5 | P | Polymorphism −265 T/C in the gene APOA2 | P | Polymorphism 668 A/G in the gene LEPR | P | |||
|---|---|---|---|---|---|---|---|---|---|
T/T | T/C + C/C | T/T | T/C + C/C | A/A | A/G + G/G | ||||
n = 139 (69.5) | n = 61 (30.5) | n = 143 (71.5) | n = 57 (28.5) | n = 63 (31.5) | n = 137 (68.5) | ||||
Clinical | |||||||||
Age (years)b | 21 (20–22) | 20 (19–22) | 0.47 | 21 (19–22) | 21 (20–22) | 0.98 | 21 (20–23) | 21 (19–22) | 0.72 |
Weight (kg)b | 74.3 (55.5–91.8) | 69.5 (58.4–88.8) | 0.76 | 74.3 (56.9–93.2) | 68.2 (55.3–89.2) | 0.80 | 75.7 (56.1–93.4) | 69.5 (56.9–90.4) | 0.94 |
BMI (kg/m2)b | 30 (21.3–33.2) | 24.4 (22–32.2) | 0.72 | 30 (21.5–33) | 24.1 (21.4–33.1) | 0.62 | 30.7 (21.3–33.2) | 24.7 (21.7–33) | 0.92 |
Waist (cm)b | 89 (78–106) | 87 (79–105.8) | 0.85 | 91.5 (79–106) | 86 (77–102.5) | 0.29 | 90 (78–106.5) | 88.2 (78–104) | 0.88 |
SBP (mmHg)a | 109.3 ± 12.7 | 111.1 ± 12.9 | 0.35 | 110 ± 12.5 | 109.4 ± 13.6 | 0.77 | 108.4 ± 11.4 | 110.5 ± 13.4 | 0.28 |
DBP (mmHg)b | 69 (64–75) | 69 (63–76) | 0.89 | 69 (63–76) | 70 (64–74) | 0.99 | 69 (63–76) | 70 (64–75) | 0.49 |
Biochemical | |||||||||
Glucose (mg/dL)b | 84 (76–89) | 82 (74–88) | 0.34 | 83 (76–89) | 83 (78–89) | 0.54 | 84 (76–89) | 83 (76–89) | 0.70 |
Cholesterol (mg/dL)b | 160 (143–185) | 150 (136–177) | 0.14 | 160 (141–182) | 157 (142–179) | 0.67 | 153 (142–171) | 162 (141–191) | 0.07 |
LDL-C (mg/dL)b | 109 (87–132) | 106 (84–125) | 0.57 | 110 (83–130) | 106 (88–131) | 0.99 | 103 (75–119) | 111 (88–138) | 0.02 |
Triglycerides (mg/dL) | 94 (69–144) | 104 (74–145) | 0.32 | 94 (70–151) | 98 (63–121) | 0.32 | 93 (63–129) | 100 (73–148) | 0.19 |
HDL-C (mg/dL)b | 45 (38–54) | 41 (35–48) | 0.02 | 44 (37–51) | 45 (37–53) | 0.95 | 43 (37–51) | 45 (37–53) | 0.50 |
Nutritional | |||||||||
Total energy (kcal/d)b | 2440 (2049–2860) | 2411 (2179–2724) | 0.79 | 2427 (2054–2854) | 2411 (2130–2822) | 0.86 | 2452 (2130–2764) | 2418 (2022–2854) | 0.72 |
Carbohydrates (g/d)b | 318 (270.8–390) | 318 (276–370) | 0.87 | 318 (277–380) | 320 (264–391) | 0.74 | 318 (278–380) | 318 (270–391) | 0.89 |
Protein (g/d)b | 105 (84–127) | 100 (85–118.2) | 0.56 | 101 (83–126) | 107 (89–125) | 0.63 | 108 (86.9–123) | 101 (83–126) | 0.46 |
Total fat (g/d)b | 81 (61–98) | 77 (65–95) | 0.58 | 78 (62–96.5) | 84 (61–97) | 0.98 | 80 (65–97) | 79 (61–96.5) | 0.69 |
SFA (g/d)b | 11 (8–16) | 11 (8–15) | 0.45 | 11 (9–15) | 10 (7–15) | 0.27 | 11 (8–14) | 11 (8–16) | 0.97 |
MUFA (g/d)b | 17 (13–24) | 16 (12–21) | 0.18 | 17 (13–23) | 16 (12–23) | 0.23 | 17 (13–23) | 17 (13–23) | 0.86 |
PUFA (g/d)b | 8 (6–12) | 10 (8–12) | 0.037 | 9 (7–13) | 8 (6–10) | 0.02 | 9 (7–12) | 9 (6–12) | 0.61 |
Cholesterol (mg/d)b | 258 (172–359) | 273 (152–329) | 0.91 | 275 (186–345) | 245 (143–328) | 0.26 | 261 (143–329) | 267 (181–357) | 0.56 |