Gene expression profiling and inhibition of adipose tissue accumulation of G. bimaculatus extract in rats on high fat diet

Ahn, Mi Young; Kim, Min-Ji; Kwon, Ryun Hee; Hwang, Jae Sam; Park, Kun-Koo

doi:10.1186/s12944-015-0113-3

Lipids in Health and Disease

Table 2 Serological findings for GB in Wistar rats on high fat diet over a 2-month treatment period

From: Gene expression profiling and inhibition of adipose tissue accumulation of G. bimaculatus extract in rats on high fat diet

Item	Unit	CON	GB100	GB200	STA	IS100
Total protein	g/dL	6.63 ± 0.18	6.75 ± 0.55	6.95 ± 0.18	6.84 ± 0.15	7.00 ± 0.11
Bilirubin	mg/dL	below 0.1	below 0.1	below 0.1	below 0.1	below 0.1
ALP	U/L	38.67 ± 4.73	38.00 ± 4.24	42.75 ± 7.14	39.00 ± 3.16	42.75 ± 8.26
AST	U/L	145.00 ± 28.58	128.50 ± 21.92	144.00 ± 98.18	96.60 ± 18.23	122.50 ± 51.86
ALT	U/L	46.67 ± 1.53	47.50 ± 10.61	81.75 ± 33.31	36.60 ± 13.13	28.50 ± 4.36
GGT	U/L	below 3	below 3	below 3	below 3	below 3
CK	U/L	607.00 ± 188.07	438.00 ± 61.00	676.25 ± 203.71	382.00 ± 36.56	256.00 ± 37.45
LDH	U/L	1577.33 ± 241.14	1830.50 ± 281.50	1897.25 ± 273.26	1179.00 ± 202.53	916.50 ± 93.39
Na	mmol/L	148.50 ± 1.32	151.50 ± 1.50	147.75 ± 1.31	147.40 ± 0.40	145.25 ± 0.85
K	mmol/L	11.20 ± 1.19	9.40 ± 2.40	10.68 ± 1.18	9.24 ± 0.95	10.43 ± 0.81
Cl	mmol/L	97.00 ± 1.08	99.00 ± 3.00	96.75 ± 1.49	98.40 ± 0.87	97.25 ± 1.03
Creatine	mg/dL	0.80 ± 0.03	0.69 ± 0.12	0.79 ± 0.05	0.72 ± 0.03	0.92 ± 0.06
BUN	mg/dL	16.57 ± 0.27	17.00 ± 0.00	19.78 ± 1.29	13.92 ± 0.46	25.73 ± 2.41
Uric acid	mg/dL	3.83 ± 0.48	7.85 ± 0.55	6.53 ± 0.47	6.08 ± 0.56	5.90 ± 0.33
T.Chol	mg/dL	106.00 ± 8.08	110.50 ± 24.50	93.00 ± 3.61	84.40 ± 3.37	100.75 ± 8.00
H.Chol	mg/dL	89.67 ± 6.17	95.50 ± 18.50	79.67 ± 2.40	74.60 ± 2.58	89.25 ± 6.16
L.Chol	mg/dL	21.00 ± 2.00	21.00 ± 17.67	17.67 ± 0.67	15.60 ± 0.81	20.00 ± 2.12
TG	mg/dL	100.50 ± 11.86	100.50 ± 0.50	101.33 ± 20.02	87.20 ± 9.25	54.25 ± 4.01
Glucose	mg/dL	187.67 ± 2.19	163.00 ± 18.00	192.75 ± 67.45	252.00 ± 29.43	198.75 ± 30.38
Ca	mg/dL	11.57 ± 0.07	11.70 ± 0.70	12.05 ± 0.37	12.30 ± 0.42	12.53 ± 0.37
IP	mg/dL	21.10 ± 1.07	19.25 ± 2.25	19.68 ± 1.77	14.44 ± 1.60	11.18 ± 0.85
FFA	uEq/L	907.49 ± 191.70	1071.50 ± 42.50	931.00 ± 81.12	855.00 ± 122.43	738.00 ± 51.22

Each value represents mean ± S.E. statistically significant from control (^* P < 0.05)

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