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Table 4 Upregulated genes differentially expressed in liver tissue of high fat diet rats treated with G. bimaculatus extract over a 1-month period

From: Gene expression profiling and inhibition of adipose tissue accumulation of G. bimaculatus extract in rats on high fat diet

 

G100a

G200b

Gene title

Gene symbol

1

0.891

1.916

glycoprotein m6a

Gpm6a

2

0.957

1.767

transmembrane protein 14A

Tmem14a

3

1.300

1.416

fatty acid synthase

Fasn

4

0.993

1.396

RT1 class I, locus CE5

RT1-CE5

5

1.370

1.393

ubiquitin-like modifier activating enzyme 5

Uba5

6

0.617

1.372

RT1 class Ib, locus EC2

RT1-EC2

7

1.101

1.358

TWIST neighbor

Twistnb

8

1.303

1.345

coagulation factor C homolog, cochlin

Coch

9

1.497

1.343

X-linked Kx blood group (McLeod syndrome) homolog

Xk

10

1.171

1.341

dedicator of cytokinesis 11

Dock11

11

0.945

1.335

amyloid beta (A4) precursor-like protein 1

Aplp1

12

0.853

1.334

D site of albumin promoter binding protein

Dbp

13

0.794

1.326

RT1 class I, locus CE11-like /// RT1 class I, locus A3

LOC100364500

14

1.860

1.319

Sumo1/sentrin/SMT3 specific peptidase 5

Senp5

15

1.125

1.316

platelet-activating factor acetylhydrolase, isoform 1b

Pafah1b1

16

1.032

1.306

isoprenoid synthase domain containing

Ispd

17

1.163

1.288

osteoglycin

Ogn

18

1.273

1.280

myxovirus (influenza virus) resistance 2

Mx2

19

0.957

1.276

similar to KIAA0802 protein

RGD1308319

20

1.170

1.276

echinoderm microtubule associated protein like 2

Eml2

21

1.061

1.275

Rab40b, member RAS oncogene family

Rab40b

22

1.099

1.268

Complement component 1, q subcomponent-like 3

C1ql3

23

1.399

1.266

family with sequence similarity 135, member A

Fam135a

24

1.377

1.266

Adipose differentiation related protein

Adfp

25

1.091

1.264

acylphosphatase 2, muscle type

Acyp2

26

1.058

1.259

RAD23 homolog B (S. cerevisiae)

Rad23b

27

1.141

1.258

cytochrome P450, family 4, subfamily v, polypeptide 3

Cyp4v3

28

1.113

1.256

Opticin

Optc

29

0.961

1.255

ubiquitin D

Ubd

30

1.038

1.253

nucleosome assembly protein 1-like 3

Nap1l3

31

1.168

1.252

protocadherin alpha 1 /// protocadherin alpha 10

Pcdha1

32

1.183

1.251

similar to CG12279-PA

LOC500420

33

1.058

1.249

solute carrier family 31 (copper transporters), member 1

Slc31a1

34

0.979

1.248

stem-loop binding protein

Slbp

35

1.026

1.242

O-sialoglycoprotein endopeptidase-like 1

Osgepl1

36

1.060

1.240

ring finger protein 141

rnf141

37

1.006

1.240

caveolin 2 /// caveolin 2-like

Cav2

38

1.025

1.240

major facilitator superfamily domain containing 9

Mfsd9

39

0.991

1.238

chemokine (C-X-C motif) ligand 9

Cxcl9

40

1.237

1.237

protein phosphatase 4, regulatory subunit 2

Ppp4r2

  1. aGB100/control ratio
  2. bGB200/control ratio