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Table 5 Downregulated genes differentially expressed in liver tissue of high fat diet rats treated with GB over a 1-month period

From: Gene expression profiling and inhibition of adipose tissue accumulation of G. bimaculatus extract in rats on high fat diet

  GB100a GB200b Gene title Gene symbol
1 0.478 0.472 chemokine (C-C motif) ligand 21b Ccl21b
2 0.563 0.563 glycosylation dependent cell adhesion molecule 1 Glycam1
3 0.610 0.583 serine (or cysteine) proteinase inhibitor, clade B, member Serpinb1a
4 0.625 0.599 T-cell receptor beta chain Tcrb
5 0.755 0.618 Lymphoid enhancer binding factor 1 Lef1
6 0.615 0.646 T-cell receptor beta chain Tcrb
7 0.646 0.658 immunoglobulin heavy chain 6 Igh-6
8 0.699 0.658 CD3 molecule, gamma polypeptide Cd3g
9 0.680 0.680 coronin, actin binding protein 1A Coro1a
10 0.687 0.687 SATB homeobox 1 Satb1
11 0.623 0.695 similar to RIKEN cDNA A430107P09 LOC100364854
12 0.717 0.701 Fas apoptotic inhibitory molecule 3 Faim3
13 0.703 0.715 lumican Lum
14 0.924 0.722 interleukin 7 receptor Il7r
15 0.815 0.731 SATB homeobox 1 Satb1
16 0.869 0.740 CD3 molecule, epsilon polypeptide Cd3e
17 0.819 0.742 ADP-ribosylation factor-like 5C Arl5c
18 0.749 0.749 protein tyrosine phosphatase, receptor type, C Ptprc
19 0.889 0.755 cancer susceptibility candidate 1 Casc1
20 0.879 0.758 LIM domain containing 2 Limd2
21 0.901 0.760 bromodomain containing 4 Brd4
22 1.007 0.764 proenkephalin Penk
23 0.776 0.765 hypothetical protein LOC100364588 LOC100364588
24 0.915 0.768 phospholipase D1 Pld1
25 0.777 0.769 immunoglobulin joining chain Igj
26 0.941 0.769 sodium channel, voltage-gated, type IV, alpha subunit Scn4a
27 0.806 0.770 Zinc finger protein 710 Znf710
28 0.729 0.770 thyroid hormone receptor beta Thrb
29 0.926 0.774 transition protein 2 Tnp2
30 0.822 0.774 SWI/SNF-related matrix-aa-dependent regulator of c2 LOC685179
31 0.958 0.774 protocadherin gamma subfamily A, 1 Pcdhga1
32 0.821 0.776 tubulin, beta 2c Tubb2c
33 0.938 0.776 galanin receptor 2 Galr2
34 0.838 0.777 matrix metallopeptidase 12 Mmp12
35 0.777 0.777 SAM and SH3 domain containing 3 Sash3
36 0.771 0.777 TBC1 domain family, member 10C Tbc1d10c
37 0.981 0.779 2′-5′-oligoadenylate synthetase-like Oasl
38 0.764 0.779 similar to immunoglobulin light chain variable region RGD1564318
39 0.812 0.779 POU class 2 associating factor 1 Pou2af1
40 0.783 0.783 CD3 molecule delta polypeptide Cd3d
  1. aGB100/control ratio
  2. bGB200/control ratio