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Table 5 Downregulated genes differentially expressed in liver tissue of high fat diet rats treated with GB over a 1-month period

From: Gene expression profiling and inhibition of adipose tissue accumulation of G. bimaculatus extract in rats on high fat diet

 

GB100a

GB200b

Gene title

Gene symbol

1

0.478

0.472

chemokine (C-C motif) ligand 21b

Ccl21b

2

0.563

0.563

glycosylation dependent cell adhesion molecule 1

Glycam1

3

0.610

0.583

serine (or cysteine) proteinase inhibitor, clade B, member Serpinb1a

4

0.625

0.599

T-cell receptor beta chain

Tcrb

5

0.755

0.618

Lymphoid enhancer binding factor 1

Lef1

6

0.615

0.646

T-cell receptor beta chain

Tcrb

7

0.646

0.658

immunoglobulin heavy chain 6

Igh-6

8

0.699

0.658

CD3 molecule, gamma polypeptide

Cd3g

9

0.680

0.680

coronin, actin binding protein 1A

Coro1a

10

0.687

0.687

SATB homeobox 1

Satb1

11

0.623

0.695

similar to RIKEN cDNA A430107P09

LOC100364854

12

0.717

0.701

Fas apoptotic inhibitory molecule 3

Faim3

13

0.703

0.715

lumican

Lum

14

0.924

0.722

interleukin 7 receptor

Il7r

15

0.815

0.731

SATB homeobox 1

Satb1

16

0.869

0.740

CD3 molecule, epsilon polypeptide

Cd3e

17

0.819

0.742

ADP-ribosylation factor-like 5C

Arl5c

18

0.749

0.749

protein tyrosine phosphatase, receptor type, C

Ptprc

19

0.889

0.755

cancer susceptibility candidate 1

Casc1

20

0.879

0.758

LIM domain containing 2

Limd2

21

0.901

0.760

bromodomain containing 4

Brd4

22

1.007

0.764

proenkephalin

Penk

23

0.776

0.765

hypothetical protein LOC100364588

LOC100364588

24

0.915

0.768

phospholipase D1

Pld1

25

0.777

0.769

immunoglobulin joining chain

Igj

26

0.941

0.769

sodium channel, voltage-gated, type IV, alpha subunit

Scn4a

27

0.806

0.770

Zinc finger protein 710

Znf710

28

0.729

0.770

thyroid hormone receptor beta

Thrb

29

0.926

0.774

transition protein 2

Tnp2

30

0.822

0.774

SWI/SNF-related matrix-aa-dependent regulator of c2

LOC685179

31

0.958

0.774

protocadherin gamma subfamily A, 1

Pcdhga1

32

0.821

0.776

tubulin, beta 2c

Tubb2c

33

0.938

0.776

galanin receptor 2

Galr2

34

0.838

0.777

matrix metallopeptidase 12

Mmp12

35

0.777

0.777

SAM and SH3 domain containing 3

Sash3

36

0.771

0.777

TBC1 domain family, member 10C

Tbc1d10c

37

0.981

0.779

2′-5′-oligoadenylate synthetase-like

Oasl

38

0.764

0.779

similar to immunoglobulin light chain variable region

RGD1564318

39

0.812

0.779

POU class 2 associating factor 1

Pou2af1

40

0.783

0.783

CD3 molecule delta polypeptide

Cd3d

  1. aGB100/control ratio
  2. bGB200/control ratio
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Lipids in Health and Disease

ISSN: 1476-511X