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Table 3 Distribution of the tag SNPs of KCNB1in case–control study

From: Association of KCNB1 polymorphisms with lipid metabolisms and insulin resistance: a case-control design of population-based cross-sectional study in Chinese Han population

SNP ID

IR(n = 199)

Non-IR(n = 534)

χ 2

P 1

P 2

OR (95 % CI)

rs926672

  

6.76

0.03

  

AA

60

182

    

AT

109

246

    

TT

24

100

    

AA vs TT

    

0.25

1.37(0.80-2.35)

AT vs TT

    

0.03

1.77(1.07-2.93)

AA vs AT

    

0.18

1.29(0.89-1.88)

Dominent model

   

0.40

0.50

1.13(0.79-1.62)

Recessive model

   

0.04

0.06

1.60(0.99-2.60)

rs2057077

  

6.33

0.04

  

CC

62

200

    

TC

111

252

    

TT

20

80

    

CC vs TT

    

0.44

0.89(0.67-1.19)

CC vs TC

    

0.11

1.35(0.94-1.95)

TT vs TC

    

0.06

0.59(0.34-1.01)

Dominent model

   

0.18

0.27

1.22(0.86-1.74)

Recessive model

   

0.11

0.13

0.66(0.39-1.12)

  1. P 1 from χ 2 test, P 2 from Logistic regression analysis and adjusted for age, gender, Dominant Model TT + AT compared with AA, Recessive Model AA + AT compared with TT for rs926672, Dominant Model TT + TC compared with CC, Recessive Model CC + TC compared with TT for rs2057077, OR odds ratio, CI confidence interval
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Lipids in Health and Disease

ISSN: 1476-511X