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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Apolipoprotein-J prevents angiotensin II-induced apoptosis in neonatal rat ventricular cells

Fig. 3

Effects of ApoJ on expression of p38 kinase and NF-κB p65 in NRVCs. a MAPK p38 expression in NRVCs. Phosphorylated MAPK p38 expression was enhanced by AngII in control infected cells, while ApoJ-transduced cells inhibited its expression (n = 3/group). b Western blot analysis of NF-κB expression in NRVCs. NRVCs were infected with control or ApoJ-expressing adenovirus for 36 h and then incubated with AngII for 24 h. Addition of AngII increased phosphorylated NF-κB expression, while ApoJ-transduced cells significantly decreased its expression (n = 3/group). *P < 0.05 versus control Ad/PBS group; **P < 0.01 versus control Ad/PBS group, # P < 0.05 versus control Ad/AngII group, ## P < 0.01 versus control Ad/AngII group

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