Table 3 Genotype distributions and allele frequencies in dyslipidemia and normal groups
From: Association of NCOA3 polymorphisms with Dyslipidemia in the Chinese Han population
SNPs | Hypercholesterolemia | Normal group | Hypertriglyceridemia | Normal group | High LDL | Normal group | Reduced HDL | Normal group |
|---|---|---|---|---|---|---|---|---|
rs10485463 | ||||||||
 CC | 48(53.9) | 199(50.9) | 87(57.6) | 160(48.6) | 35(49.3) | 212(51.8) | 61(44.5) | 186(54.2) |
 CG | 33(37.1) | 160(40.9) | 54(35.8) | 139(42.2) | 30(42.3) | 163(39.9) | 58(42.3) | 135(39.4) |
 GG | 8(9.0) | 32(8.2) | 10(6.6) | 30(9.1) | 6(8.5) | 34(8.3) | 18(13.1) | 22(6.4) |
  χ 2 | 0.452 |  | 3.48 |  | 0.164 |  | 7.319 |  |
 P | 0.798 |  | 0.175 |  | 0.921 |  | 0.026 |  |
 C | 129(72.5) | 558(71.4) | 228(75.5) | 459(69.8) | 100(70.4) | 587(71.8) | 180(65.7) | 507(73.9) |
 G | 49(27.5) | 224(28.6) | 74(24.5) | 199(30.2) | 42(29.6) | 231(28.2) | 94(34.3) | 179(26.1) |
  χ 2 | 0.089 |  | 3.351 |  | 0.106 |  | 6.49 |  |
 P | 0.766 |  | 0.067 |  | 0.744 |  | 0.011 |  |
rs2425955 | ||||||||
 GG | 57(60.0) | 212(51.0) | 99(62.3) | 170(48.3) | 42(52.5) | 227(52.7) | 81(54.4) | 188(51.9) |
 GT | 34(35.8) | 172(41.3) | 54(34.0) | 152(43.2) | 35(43.8) | 171(39.7) | 58(38.9) | 148(40.9) |
 TT | 4(4.2) | 32(7.7) | 6(3.8) | 30(8.5) | 3(3.8) | 33(7.7) | 10(6.7) | 26(7.2) |
  χ 2 | 3.123 |  | 9.876 |  | 1.740 |  | 0.252 |  |
 P | 0.210 |  | 0.007 |  | 0.419 |  | 0.882 |  |
 G | 148(77.9) | 596(71.6) | 252(79.2) | 492(69.9) | 119(74.4) | 625(72.5) | 220(73.8) | 534(72.4) |
 T | 42(22.1) | 236(28.4) | 66(20.8) | 212(30.1) | 41(25.6) | 237(27.5) | 78(26.2) | 200(27.6) |
  χ 2 | 3.061 |  | 9.689 |  | 0.238 |  | 0.224 |  |
 P | 0.080 |  | 0.002 |  | 0.626 |  | 0.636 |  |
rs6066394 | ||||||||
 TT | 49(52.7) | 168(40.8) | 81(51.9) | 138(39.0) | 36(45.6) | 181(42.5) | 67(45.6) | 150(41.9) |
 CT | 33(35.5) | 190(46.1) | 56(35.9) | 167(47.9) | 35(44.3) | 188(44.1) | 63(42.9) | 160(44.7) |
 CC | 11(11.8) | 54(13.1) | 19(12.2) | 46(13.2) | 8(10.1) | 57(13.4) | 17(11.6) | 48(13.4) |
  χ 2 | 4.554 |  | 7.783 |  | 0.696 |  | 0.683 |  |
 P | 0.103 |  | 0.020 |  | 0.706 |  | 0.711 |  |
 T | 131(70.4) | 526(63.8) | 218(69.9) | 443(63.1) | 107(67.7) | 550(64.6) | 197(67.0) | 460(64.2) |
 C | 55(29.6) | 298(36.2) | 94(30.1) | 259(36.9) | 51(32.3) | 302(35.4) | 97(33.0) | 256(35.8) |
  χ 2 | 2.903 |  | 4.618 |  | 0.588 |  | 0.699 |  |
 P | 0.088 |  | 0.032 |  | 0.443 |  | 0.403 |  |
rs6094753 | ||||||||
 GG | 60(61.9) | 223(52.8) | 101(63.5) | 182(50.6) | 44(53.7) | 239(54.7) | 86(55.5) | 197(54.1) |
 GA | 30(30.9) | 171(40.5) | 52(32.7) | 149(41.4) | 32(39.0) | 169(38.7) | 56(36.1) | 145(39.8) |
 AA | 7(7.2) | 28(6.6) | 6(3.8) | 29(8.1) | 6(7.3) | 29(6.6) | 13(8.4) | 22(6.0) |
  χ 2 | 3.089 |  | 8.547 |  | 0.063 |  | 1.308 |  |
 P | 0.213 |  | 0.014 |  | 0.969 |  | 0.520 |  |
 G | 150(77.3) | 617(73.1) | 254(79.9) | 513(71.2) | 120(73.2) | 647(74.0) | 228(73.5) | 539(74.0) |
 A | 44(22.7) | 227(26.9) | 64(20.1) | 207(28.8) | 44(26.8) | 227(26.0) | 82(26.5) | 189(26.0) |
  χ 2 | 1.453 |  | 8.504 |  | 0.053 |  | 0.027 |  |
 P | 0.228 |  | 0.004 |  | 0.819 |  | 0.869 |  |