Skip to main content

Table 4 Odds ratios for the likelihood of dyslipidemia according to NCOA3 polymorphisms

From: Association of NCOA3 polymorphisms with Dyslipidemia in the Chinese Han population

SNPs

Hypercholesterolemia

Hypertriglyceridemia

High LDL

Reduced HDL

 

OR(95 % CI)

ORa(95 % CI)

OR(95 % CI)

ORa(95 % CI)

OR(95 % CI)

ORa(95 % CI)

OR(95 % CI)

ORa(95 % CI)

rs10485463

 CC

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

 CG

0.85(0.52–1.39)

0.87(0.53–1.42)

0.71(0.47–1.07)

0.70(0.47–1.06)

1.11(0.66–1.89)

1.15(0.67–1.96)

1.31(0.86–2.00)

1.28(0.83–1.97)

 GG

1.04(0.45–2.39)

1.09(0.47–2.54)

0.61(0.29–1.31)

0.57(0.26–1.23)

1.07(0.42–2.73)

1.19(0.46–3.07)

2.49(1.25–4.96)

2.27(1.12–4.61)

 C

1.00

 

1.00

 

1.00

 

1.00

 

 G

0.95(0.66–1.36)

 

0.75(0.55–1.02)

 

1.07(0.72–1.58)

 

1.48(1.09–2.00)

 

rs2425955

 GG

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

 GT

0.73(0.46–1.18)

0.75(0.47–1.20)

0.61(0.41–0.91)

0.60(0.40–0.89)

1.11(0.68–1.81)

1.14(0.70–1.87)

0.91(0.61–1.36)

0.87(0.57–1.31)

 TT

0.46(0.16–1.37)

0.46(0.16–1.36)

0.34(0.14–0.85)

0.34(0.14–0.86)

0.49(0.14–1.68)

0.49(0.14–1.67)

0.89(0.41–1.94)

0.89(0.40–1.97)

 G

1.00

 

1.00

 

1.00

 

1.00

 

 T

0.72(0.49–1.04)

 

0.61(0.44–0.83)

 

0.91(0.62–1.33)

 

0.93(0.68–1.26)

 

rs6066394

 TT

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

 CT

0.59(0.37–0.97)

0.61(0.37–1.00)

0.56(0.37–0.85)

0.55(0.37–0.83)

0.94(0.56–1.56)

0.97(0.58–1.62)

0.88(0.58–1.33)

0.83(0.54–1.26)

 CC

0.70(0.34–1.44)

0.70(0.34–1.44)

0.69(0.38–1.26)

0.70(0.38–1.27)

0.71(0.31–1.60)

0.70(0.31–1.60)

0.79(0.42–1.48)

0.79(0.42–1.50)

 T

1.00

 

1.00

 

1.00

 

1.00

 

 C

0.74(0.52–1.05)

 

0.73(0.54–0.97)

 

0.87(0.60–1.25)

 

0.88(0.66–1.18)

 

rs6094753

 GG

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

 GA

0.65(0.40–1.05)

0.66(0.41–1.07)

0.63(0.42–0.94)

0.62(0.41–0.92)

1.03(0.63–1.69)

1.06(0.64–1.74)

0.88(0.59–1.32)

0.84(0.56–1.26)

 AA

0.93(0.39–2.23)

0.92(0.38–2.21)

0.37(0.15–0.93)

0.37(0.15–0.94)

1.12(0.44–2.86)

1.11(0.43–2.85)

1.35(0.65–2.81)

1.42(0.67–3.00)

 G

1.00

 

1.00

 

1.00

 

1.00

 

 A

0.80(0.55–1.15)

 

0.62(0.45–0.86)

 

1.04(0.72–1.52)

 

1.03(0.76–1.39)

 
  1. aORs and 95 % CI were adjusted for age and sex