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Table 3 Stratification analysis of APOA1 -75 G/A polymorphisms in renal cancer cases

From: Apolipoprotein A1 -75 G/A and +83 C/T polymorphisms and renal cancer risk

 

Cases

GG

GA

AA

n (%)

OR (95 %CI)

P

n (%)

OR (95 %CI)

P

n (%)

OR (95 %CI)

P

Grade

216

108 (50.0)

1 (Reference)

 

66 (30.6)

1 (Reference)

 

42 (19.4)

1 (Reference)

 

 1

55

28 (50.9)

1.02 (0.61,1.70)

0.95

15 (27.3)

0.89 (0.47,1.68)

0.73

12 (21.8)

1.12 (0.55,2.27)

0.75

 2

129

64 (49.6)

0.99 (0.68,1.45)

0.97

42 (32.6)

1.07 (0.68,1.66)

0.78

23 (17.8)

0.92 (0.53,1.59)

0.76

 3 + 4

32

16 (50.0)

1.00 (0.53,1.90)

1.00

9 (28.1)

0.92 (0.42,2.03)

0.84

7 (21.9)

1.13 (0.47,2.72)

0.79

Tumor classification

216

108 (50.0)

1 (Reference)

 

66 (30.6)

1 (Reference)

 

42 (19.4)

1 (Reference)

 

 T1

103

55 (53.4)

1.07 (0.72,1.59)

0.75

29 (28.2)

0.92 (0.56,1.51)

0.75

19 (18.4)

0.95 (0.53,1.71)

0.86

 T2

49

22 (44.9)

0.90 (0.52,1.56)

0.70

16 (32.7)

1.07 (0.57,2.00)

0.84

11 (22.4)

1.16 (0.56,2.40)

0.70

 T3

57

28 (49.1)

0.98 (0.59,1.63)

0.95

19 (33.3)

1.09 (0.61,1.96)

0.77

10 (17.6)

0.90 (0.43,1.91)

0.79

 T4

7

3 (42.8)

0.86 (0.22,3.38)

0.83

2 (28.6)

0.94 (0.19,4.61)

0.93

2 (28.6)

1.47 (0.29,7.32)

0.64

Lymph node invasion status

216

108 (50.0)

1 (Reference)

 

66 (30.6)

1 (Reference)

 

42 (19.4)

1 (Reference)

 

 Negative

199

99 (49.7)

0.99 (0.71,1.39)

0.98

61 (30.7)

1.00 (0.67,1.49)

0.99

39 (19.6)

1.01 (0.63,1.62)

0.97

 Positive

17

9 (52.9)

1.06 (0.46,2.45)

0.89

5 (29.4)

0.96 (0.34,2.71)

0.94

3 (17.7)

0.91 (0.26,3.24)

0.88

Distant metastasis status

216

108 (50.0)

1 (Reference)

 

66 (30.6)

1 (Reference)

 

42 (19.4)

1 (Reference)

 

 Negative

188

99 (52.7)

1.05 (0.75,1.47)

0.76

59 (31.4)

1.03 (0.69,1.54)

0.90

30 (15.9)

0.82 (0.49,1.36)

0.45

 Positive

28

9 (32.1)

0.64 (0.29,1.41)

0.27

7 (25.0)

0.82 (0.34,1.96)

0.65

12 (42.9)

2.20 (1.04,4.68)

0.04

Pathology

216

108 (50.0)

1 (Reference)

 

66 (30.6)

1 (Reference)

 

42 (19.4)

1 (Reference)

 

 Clear cell carcinoma

197

99 (50.2)

1.01 (0.72,1.40)

0.98

60 (30.5)

1.00 (0.67,1.49)

0.99

38 (19.3)

0.99 (0.61,1.60)

0.97

 Granular cell carcinoma

15

7 (46.7)

0.93 (0.37,2.36)

0.88

5 (33.3)

1.09 (0.38,3.11)

0.87

3 (20.0)

1.03 (0.29,3.71)

0.97

 Chromophobe cell carcinoma

4

2 (50.0)

1.00 (0.18,5.55)

1.00

1 (25.0)

0.82 (0.09,7.45)

0.86

1 (25.0)

1.29 (0.14,11.79)

0.82