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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Mevalonate inhibits acid sphingomyelinase activity, increases sphingomyelin levels and inhibits cell proliferation of HepG2 and Caco-2 cells

Fig. 2

Kinetic changes of acid SMase in HepG2 cells in the absence and presence of mevalonate. The cells were subcultured in different wells for different time point examinations. One day after subculture, mevalonates at 0, 10 and 20 mM were added to the wells followed by incubation for 8, 24, 48 and 72 h. The acid SMase activities were determined at different time points. Results are means ± SD from triple wells for each time points in separated three experiments. **p < 0.01, ***p < 0.005 compared with 0 concentration

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Lipids in Health and Disease

ISSN: 1476-511X