Fig. 5From: Mevalonate inhibits acid sphingomyelinase activity, increases sphingomyelin levels and inhibits cell proliferation of HepG2 and Caco-2 cellsCell proliferation after mevalonate treatment. Both HepG2 and Caco-2 cells were incubated with mevalonate for 48 h. The cell proliferation was determined by a kit from Trevigen, which was based on MTT reagent. Results are means ± SD from triple cultured wells in three separate experiments and expressed as percentage of the control. ***P < 0.005 compared with controlBack to article page