Supplementation of krill oil with high phospholipid content increases sum of EPA and DHA in erythrocytes compared with low phospholipid krill oil

Ramprasath, V. R.; Eyal, I.; Zchut, S.; Shafat, I.; Jones, P. J. H.

doi:10.1186/s12944-015-0142-y

Lipids in Health and Disease

Table 2 Plasma fatty acids concentrations during each of the experimental phases

From: Supplementation of krill oil with high phospholipid content increases sum of EPA and DHA in erythrocytes compared with low phospholipid krill oil

Fatty acids (%)	Treatment	Baseline	Endpoint	Change (Difference)
C20:5n-3 Eicosapentaenoic acid (EPA)	HPL Krill oil	0.79 ± 0.07	2.05 ± 0.12^a	1.26 ± 0.11^a
	LPL krill oil	0.76 ± 0.06	1.98 ± 0.11^a	1.23 ± 0.13^a
	Control	0.88 ± 0.08	0.76 ± 0.10	−0.12 ± 0.07
C22:5n-3 Docosapentaenoic acid (DPA)	HPL Krill oil	0.63 ± 0.07	0.78 ± 0.06^ab	0.15 ± 0.05^a
	LPL krill oil	0.76 ± 0.04	0.98 ± 0.05^a	0.22 ± 0.04^a
	Control	0.65 ± 0.06	0.61 ± 0.04	−0.04 ± 0.05
C22:6n-3 Docosahexaenoic acid (DHA)	HPL Krill oil	2.97 ± 0.13	3.99 ± 0.19^ab	1.01 ± 0.15^a
	LPL krill oil	3.06 ± 0.12	4.35 ± 0.22^a	1.29 ± 0.13^a
	Control	3.15 ± 0.14	2.90 ± 0.13	−0.25 ± 0.16
Total SFA	HPL Krill oil	43.36 ± 0.44	42.80 ± 0.35^b	−0.57 ± 0.45^b
	LPL krill oil	44.99 ± 0.66	41.83 ± 0.34	−3.16 ± 0.72^a
	Control	41.69 ± 1.11	42.49 ± 0.37	0.79 ± 1.12
Total MUFA	HPL Krill oil	17.58 ± 0.68	16.44 ± 0.57	−1.13 ± 0.68^b
	LPL krill oil	12.73 ± 1.31	15.65 ± 0.47^a	2.92 ± 1.30
	Control	17.63 ± 0.70	16.96 ± 0.51	−0.67 ± 0.68
Total PUFA	HPL Krill oil	39.06 ± 0.54	40.76 ± 0.44^b	1.70 ± 0.55
	LPL krill oil	42.27 ± 0.77	42.52 ± 0.47^a	0.25 ± 0.77
	Control	40.68 ± 0.94	40.56 ± 0.46	−0.12 ± 1.12
Total n-6 PUFA	HPL Krill oil	34.04 ± 0.54	33.36 ± 0.45^a	−0.68 ± 0.43^b
	LPL krill oil	37.09 ± 0.77	34.61 ± 0.59	−2.48 ± 0.67^a
	Control	35.40 ± 0.86	35.70 ± 0.42	0.30 ± 0.96
Total n-3 PUFA	HPL Krill oil	5.02 ± 0.16	7.40 ± 0.28^a	2.38 ± 0.24^a
	LPL krill oil	5.19 ± 0.16	7.91 ± 0.32^a	2.72 ± 0.27^a
	Control	5.28 ± 0.21	4.86 ± 0.15	−0.42 ± 0.20
n-6:n-3	HPL Krill oil	6.93 ± 0.27	4.69 ± 0.26^a	−2.25 ± 0.23^a
	LPL krill oil	7.29 ± 0.29	4.58 ± 0.27^a	−2.72 ± 0.19^a
	Control	6.87 ± 0.28	7.46 ± 0.23	0.59 ± 0.17
EPA + DHA	HPL Krill oil	3.76 ± 0.15	6.04 ± 0.28^a	2.27 ± 0.22^a
	LPL krill oil	3.82 ± 0.14	6.33 ± 0.30^a	2.51 ± 0.23^a
	Control	4.03 ± 0.19	3.66 ± 0.13	−0.37 ± 0.18

Values are expressed as Mean ± SEM. n = 20. ^a and ^b denote significance compared with control or LPL krill oil interventions respectively

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