Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 1 Main characteristics of studies involved in this meta-analysis of PCSK9 E670G polymorphism and CAD risk

From: The associations between proprotein convertase subtilisin/kexin type 9 E670G polymorphism and the risk of coronary artery disease and serum lipid levels: a meta-analysis

First author Year Country Ethnicity Mean age (years) (case/control) Type of study Sample size (case/control) Cases Controls Genotyping method MAF (control, %) HWE (P)
AA AG GG AA AG GG
Salazar LA [16] 2007 Chile Caucasian -/ - C-C 110/108 105 5 0 103 5 0 PCR-RFLP 2.3 >0.05
Hsu LA [10] 2009 China Asian 55.6 + 10.5/ 45.9 + 10.4 C-C 202/614 182 20 0 541 72 1 PCR-RFLP 6.0 >0.05
Zeng J [19] 2011 China Asian 65.9 ± 10.2/ 57.0 ± 8.7 C-C 212/184 167 38 7 165 17 2 PCR-RFLP 5.7 >0.05
Meng YH [7] 2011 China Asian 66.49 ± 9.92/ 64.34 ± 15.35 C-C 165/180 146 19 0 166 14 0 PCR-RFLP 3.9 >0.05
Slimani A [8] 2014 Tunisian African 61[55–67]/ 49[45–55] C-C 192/232 148 37 7 199 32 1 PCR-RFLP 7.3 >0.05
Zhang L [23] 2014 China Asian 59.85 + 8.71/ 58.83 + 9.35 C-C 416/257 291 117 8 212 42 3 PCR-RFLP 15.3 >0.05
Mo YQ [26] 2015 China Asian 56.4 + 11.7/ 54.7 + 10.2 C-C 100/100 87 13 0 92 8 0 DNA sequencing 4.0 >0.05
Gao Y a [25] 2015 China Asian -/- C-C 60/60 19 21 20 20 22 18 PCR-RFLP 48.3 <0.05
Gao Y b [25] 2015 China Asian -/- C-C 60/60 15 21 24 23 18 19 PCR-RFLP 46.7 <0.05
  1. aChinese Han population
  2. bMongols population
  3. C-C case–control, PCR-RFLP polymerase chain reaction- restriction fragment length polymorphism, MAF minor allelic frequencies, HWE Hardy-Weinberg equilibrium