From: Effects of pitavastatin add-on therapy on chronic kidney disease with albuminuria and dyslipidemia
 | Diet (n = 14) | Diet-plus-statin (n = 14) | P value |
---|---|---|---|
Age (years) | 63.9 ± 3.3 | 60.6 ± 3.4 | 0.492 |
Gender (female/male) | 4/10 | 4/10 | 0.661 |
Body mass Index (kg/m2) | 24.4 ± 0.7 | 24.3 ± 0.9 | 0.934 |
Current smoking (n (%)) | 1 (7) | 2 (14) | 0.500 |
Alcohol (n (%)) | 4 (29) | 3 (21) | 0.500 |
Diabetes mellitus (n (%)) | 4 (29) | 5 (36) | 0.500 |
Hypertention (n (%)) | 12 (86) | 12 (86) | 0.702 |
Cerebrovascular disease (n (%)) | 0 (0) | 1 (7) | 0.500 |
Ischemic heart disease (n (%)) | 0 (0) | 1 (7) | 0.500 |
Cause of CKD (n (%)): | Â | Â | 0.318 |
 Diabetic nephropathy | 1 (7) | 2 (14) |  |
 Chronic glomerulonephritis | 6 (43) | 7 (50) |  |
 Nephrosclerosis | 6 (43) | 4 (29) |  |
 Others | 1 (7) | 1 (7) |  |
Systolic BP (mmHg) | 133 ± 4 | 127 ± 4 | 0.306 |
Diastolic BP (mmHg) | 79 ± 2 | 76 ± 2 | 0.435 |
Heart rate (beats/min) | 69 ± 3 | 74 ± 2 | 0.239 |
Plasma glucose (mg/dL) | 113 ± 7 | 107 ± 4 | 0.614 |
HbA1c (%) | 5.6 ± 0.1 | 5.6 ± 0.1 | 0.946 |
TC (mg/dL) | 211 ± 6 | 207 ± 7 | 0.620 |
LDL-C (mg/dL) | 139 ± 6 | 136 ± 6 | 0.797 |
HDL-C (mg/dL) | 56 ± 3 | 56 ± 4 | 0.966 |
TG (mg/dL) | 145 ± 14 | 154 ± 20 | 0.715 |
AST (U/L) | 24 ± 1 | 20 ± 1 | 0.035 |
ALT (U/L) | 22 ± 2 | 20 ± 3 | 0.265 |
Creatine kinase (U/L) | 110 ± 13 | 106 ± 13 | 0.946 |
Serum creatinine (mg/dL) | 1.2 ± 0.1 | 1.3 ± 0.1 | 0.593 |
Estimated GFR (mL/min/1.73 m2) | 50.1 ± 4.9 | 48.6 ± 4.7 | 0.827 |
GFR category (n (%)): | Â | Â | 0.500 |
 G1 | 1 (7) | 0 (0) |  |
 G2 | 2 (14) | 4 (29) |  |
 G3a | 5 (36) | 3 (21) |  |
 G3b | 5 (36) | 6 (43) |  |
 G4 | 1 (7) | 1 (7) |  |
 G5 | 0 (0) | 0 (0) |  |
UACR (mg/g-Cr) | 1025 ± 465 | 801 ± 254 | 0.946 |
Albuminuria category (n (%)): | Â | Â | 1.000 |
 A2 | 7 (50) | 7 (50) |  |
 A3 | 7 (50) | 7 (50) |  |