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Table 1 Demographic characteristics of the study groups at baseline

From: Effects of pitavastatin add-on therapy on chronic kidney disease with albuminuria and dyslipidemia

 

Diet (n = 14)

Diet-plus-statin (n = 14)

P value

Age (years)

63.9 ± 3.3

60.6 ± 3.4

0.492

Gender (female/male)

4/10

4/10

0.661

Body mass Index (kg/m2)

24.4 ± 0.7

24.3 ± 0.9

0.934

Current smoking (n (%))

1 (7)

2 (14)

0.500

Alcohol (n (%))

4 (29)

3 (21)

0.500

Diabetes mellitus (n (%))

4 (29)

5 (36)

0.500

Hypertention (n (%))

12 (86)

12 (86)

0.702

Cerebrovascular disease (n (%))

0 (0)

1 (7)

0.500

Ischemic heart disease (n (%))

0 (0)

1 (7)

0.500

Cause of CKD (n (%)):

  

0.318

 Diabetic nephropathy

1 (7)

2 (14)

 

 Chronic glomerulonephritis

6 (43)

7 (50)

 

 Nephrosclerosis

6 (43)

4 (29)

 

 Others

1 (7)

1 (7)

 

Systolic BP (mmHg)

133 ± 4

127 ± 4

0.306

Diastolic BP (mmHg)

79 ± 2

76 ± 2

0.435

Heart rate (beats/min)

69 ± 3

74 ± 2

0.239

Plasma glucose (mg/dL)

113 ± 7

107 ± 4

0.614

HbA1c (%)

5.6 ± 0.1

5.6 ± 0.1

0.946

TC (mg/dL)

211 ± 6

207 ± 7

0.620

LDL-C (mg/dL)

139 ± 6

136 ± 6

0.797

HDL-C (mg/dL)

56 ± 3

56 ± 4

0.966

TG (mg/dL)

145 ± 14

154 ± 20

0.715

AST (U/L)

24 ± 1

20 ± 1

0.035

ALT (U/L)

22 ± 2

20 ± 3

0.265

Creatine kinase (U/L)

110 ± 13

106 ± 13

0.946

Serum creatinine (mg/dL)

1.2 ± 0.1

1.3 ± 0.1

0.593

Estimated GFR (mL/min/1.73 m2)

50.1 ± 4.9

48.6 ± 4.7

0.827

GFR category (n (%)):

  

0.500

 G1

1 (7)

0 (0)

 

 G2

2 (14)

4 (29)

 

 G3a

5 (36)

3 (21)

 

 G3b

5 (36)

6 (43)

 

 G4

1 (7)

1 (7)

 

 G5

0 (0)

0 (0)

 

UACR (mg/g-Cr)

1025 ± 465

801 ± 254

0.946

Albuminuria category (n (%)):

  

1.000

 A2

7 (50)

7 (50)

 

 A3

7 (50)

7 (50)

 
  1. Values are means ± SE or number (percentage). CKD chronic kidney disease, BP blood pressure, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglyceride, AST aspartate transaminase, ALT alanine transaminase, GFR glomerular filtration rate, UACR urine albumin-to-creatinine ratio