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Table 4 Comparison of the parameters of renal function and oxidative stress in the diet therapy and diet-plus-statin groups

From: Effects of pitavastatin add-on therapy on chronic kidney disease with albuminuria and dyslipidemia

 

Diet

Diet-plus-statin

 

Baseline

6 months

12 months

Baseline

6 months

12 months

Renal function:

      

 Estimated GFR (mL/min/1.73 m2)

50.1 ± 4.9

45.1 ± 4.3*

45.9 ± 4.3*

48.6 ± 4.7

45.6 ± 4.5*

45.1 ± 5.3*

 UACR (mg/g-Cr)

1025 ± 465

671 ± 220

687 ± 249

801 ± 254

714 ± 233

557 ± 186

Oxidative stress:

      

 Pentosidine (ng/mL)

40 ± 4

28 ± 3*

24 ± 3*

46 ± 7

38 ± 7

34 ± 6*

  1. Values are means ± SE. GFR glomerular filtration rate, UACR urine albumin-to-creatinine ratio. *P < 0.05 vs baseline