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Table 4 Comparison of the parameters of renal function and oxidative stress in the diet therapy and diet-plus-statin groups

From: Effects of pitavastatin add-on therapy on chronic kidney disease with albuminuria and dyslipidemia

  Diet Diet-plus-statin
  Baseline 6 months 12 months Baseline 6 months 12 months
Renal function:       
 Estimated GFR (mL/min/1.73 m2) 50.1 ± 4.9 45.1 ± 4.3* 45.9 ± 4.3* 48.6 ± 4.7 45.6 ± 4.5* 45.1 ± 5.3*
 UACR (mg/g-Cr) 1025 ± 465 671 ± 220 687 ± 249 801 ± 254 714 ± 233 557 ± 186
Oxidative stress:       
 Pentosidine (ng/mL) 40 ± 4 28 ± 3* 24 ± 3* 46 ± 7 38 ± 7 34 ± 6*
  1. Values are means ± SE. GFR glomerular filtration rate, UACR urine albumin-to-creatinine ratio. *P < 0.05 vs baseline