Single nucleotide polymorphism rs3774261 in the AdipoQ gene is associated with the risk of coronary heart disease (CHD) in Northeast Han Chinese population: a case-control study

Table 3 Lipid profiles in different carriers of ADIPOQ genotypes and alleles in controls

Variable	No.	TG (mmol/L)	TC (mmol/L)	LDL-C (mmol/L)	HDL-C (mmol/L)
rs3774261	n
AA	274	1.21 ± 0.67	4.11 ± 0.81	2.65 ± 0.71	1.30 ± 0.24
AG	350	1.27 ± 0.68	4.14 ± 0.81	2.63 ± 0.74	1.32 ± 0.25
GG	136	1.24 ± 0.59	4.04 ± 0.78	2.55 ± 0.66	1.31 ± 0.26
P ^a		0.513	0.330	0.424	0.572
AA + AG	486	1.27 ± 0.66	4.12 ± 0.80	2.61 ± 0.72	1.32 ± 0.26
P ^b		0.292	0.669	0.517	0.323
rs1063537	n
TT	56	1.34 ± 0.94	4.06 ± 0.65	2.55 ± 0.58	1.32 ± 0.27
CT	319	1.23 ± 0.65	4.13 ± 0.80	2.64 ± 0.72	1.31 ± 0.24
CC	385	1.25 ± 0.62	4.10 ± 0.83	2.62 ± 0.73	1.31 ± 0.26
P ^a		0.521	0.767	0.684	0.966
TT + CT	375	1.24 ± 0.70	4.12 ± 0.78	2.63 ± 0.70	1.31 ± 0.24
P ^c		0.850	0.769	0.914	0.932
rs2082940	n
TT	63	1.32 ± 0.91	4.05 ± 0.62	2.55 ± 0.57	1.32 ± 0.27
CT	323	1.20 ± 0.60	4.11 ± 0.80	2.63 ± 0.73	1.31 ± 0.24
CC	374	1.28 ± 0.67	4.12 ± 0.84	2.63 ± 0.73	1.32 ± 0.26
P ^a		0.195	0.785	0.663	0.953
TT + CT	386	1.22 ± 0.66	4.10 ± 0.77	2.62 ± 0.71	1.31 ± 0.25
P ^c		0.235	0.717	0.831	0. 815

P ^a, comparisons among all gennotypes; P ^b, minor allele homozygote serves as the reference; P ^c, major allele homozygote serves as the reference. P values were calculated with ANCOVA adjusted for age, and sex

ISSN: 1476-511X