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Table 5 Associations between AdipoQ gene polymorphisms and CHD risk

From: Single nucleotide polymorphism rs3774261 in the AdipoQ gene is associated with the risk of coronary heart disease (CHD) in Northeast Han Chinese population: a case-control study

SNPs Models OR 95%CI P AIC
rs3774261 Codominant 1.68 1.32–2.13 <0.0001 2058.1
   1.90 1.41–2.54 <0.0001  
  Dominant 1.74 1.39–2.18 <0.0001 2056.9
  Recessive 1.37 1.07–1.77 0.014 2074.6
  Overdominant 1.29 1.06–1.59 0.013 2074.5
  Log-additive 1.40 1.21–1.62 <0.0001 2059.7
rs1063537 Codominant 0.84 0.68–1.04 0.112 2082.9
   0.88 0.59–1.32 0.531  
  Dominant 0.85 0.69–1.04 0.11 2080.9
  Recessive 0.95 0.64–1.40 0.78 2083.4
  Overdominant 0.85 0.70–1.05 0.14 2081.3
  Log-additive 0.89 0.76–1.05 0.16 2081.5
rs2082940 Codominant 0.81 0.66–1.00 0.056 2078.1
   0.76 0.51–1.13 0.179  
  Dominant 0.80 0.66–0.99 0.035 2076.2
  Recessive 0.83 0.57–1.23 0.360 2079.8
  Overdominant 0.84 0.68–1.03 0.1 2077.9
  Log-additive 0.84 0.72–0.99 0.04 2076.4
  1. OR odds ratio, CI confidence interval, AIC akaike information criterion. Codominant model (homozygote for the major allele serves as the reference); Dominant model (minor allele homozygote + heterozygote vs. major allele homozygote); Recessive model (minor allele homozygote vs. major allele homozygote + heterozygote); Overdominant model (heterozygote GA vs homozygote AA + GG serve as reference); Log-additive model (compares the relative significance of the minor allele : 0,1,2 in AA, AG, and GG respectively for the G allele of rs3774261; and 0,1,2 in CC, CT, and TT respectively for the T allele of rs1063537 and rs2082940). Bold values are statistically significant.
  2. Unconditional logistic regression was used for data analyses. Age and sex, were adjusted during analyses. Bonferroni correction value =0.008 (0.05/6 = 0.008)