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Table 8 ORs to develop CHD with different genotypes of three polymorphisms and plasma triglycerides (TG) levels*

From: Single nucleotide polymorphism rs3774261 in the AdipoQ gene is associated with the risk of coronary heart disease (CHD) in Northeast Han Chinese population: a case-control study

Lipid levels (mmol/L)

rs3774261

rs1063537

rs2082940

AA

AG

GG

CC

CT

TT

CC

CT

TT

TG < 1.70

1.00a

2.15 (1.64-2.83)

1.87 (1.34-2.62)

1.00a

0.91 (0.71-1.16)

0.75 (0.47-1.18)

1.00a

0.85 (0.66-1.08)

0.65 (0.41-1.02)

1.70 ≤ TG < 2.26

9.45 (4.04-22.08)

3.74 (2.30-6.08)

19.68 (5.86-66.03)

3.80 (2.21-6.51)

2.42 (1.43-4.09)

---

3.24 (1.92-5.48)

2.56 (1.49-4.39)

---

TG ≥ 2.26

4.55 (2.32-8.89)

2.59 (1.62-4.13)

14.87 (5.10-43.37)

2.91 (1.79-4.72)

1.44 (0.87-2.38)

4.86 (1.02-23.12)

2.70 (1.67-4.35)

1.48 (0.89-2.48)

3.10 (0.81-11.79)

P-value**

<0.0001

0.014

0.031

  1. *Interactions with other lipid profiles, diabetes, hypertension, smoking and alcohol drinking were not statistically significant (data not shown)
  2. aThis group was the reference group
  3. **Interaction between each polymorphism and plasma TG levels; unconditional logistic regression adjusted for age and sex was used in calculating OR, 95 %CI, and P-values of interactions. Bold values are statistically significant