Table 3 Genotype and allele frequencies of rs5888 polymorphism in the SCARB1 gene according to CAD status in whole study group and in subgroups separated by gender
non- CAD patients | CAD patients | P-value* | |||||||
|---|---|---|---|---|---|---|---|---|---|
All (n = 546) | Male (n = 243) | Female (n = 303) | All (n = 505) | Male (n = 234) | Female (n = 271) | All | Male | Female | |
rs5888 (C > T) | 0.163 | 0.781 | 0.143 | ||||||
CC | 195 (35.7) | 88 (36.2) | 107 (35.3) | 162 (32.1) | 81 (34.6) | 81 (29.9) | |||
CT | 281 (51.5) | 121 (49.8) | 160 (52.8) | 259 (51.3) | 115 (49.1) | 144 (53.1) | |||
TT | 70 (12.8) | 34 (14.0) | 36 (11.9) | 84 (16.6) | 38 (16.2) | 46 (17.0) | |||
CT + TT | 351 (64.3) | 155 (63.8) | 196 (64.7) | 343 (67.9) | 153 (65.4) | 190 (70.9) | 0.214 | 0.715 | 0.167 |
Alleles | 0.082 | 0.544 | 0.070 | ||||||
C | 671 (61.4) | 297 (61.1) | 374 (61.7) | 583 (57.7) | 277 (59.2) | 306 (56.5) | |||
T | 421 (38.6) | 189 (38.9) | 232 (38.3) | 427 (42.3) | 191 (40.8) | 236 (43.5) | |||