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Table 4 Demographic and laboratory characteristics of patients according to RRT allocation and ApoE Δ4 allele presence

From: Apolipoprotein E polymorphism modulation of asymmetric dimethylarginine in hypertensive patients is determined by renal function

 

In RRT

 

Not in RRT

 
 

Δ4 allele (+) (N = 40)

Δ4 allele (−) (N = 158)

P

Δ4 allele (+) (N =74)

Δ4 allele (−) (N = 330)

P

Age (years)

52.47 ± 14.97

53.60 ± 14.36

0.669*

62.80 ± 13.36

63.81 ± 11.72

0.511*

Dialysis vintage

38.95 ± 24.24

37.22 ± 27.69

0.697*

-

-

 

Male

25 (21.6 %)

91 (78.4 %)

0.574**

37 (19.7 %)

151 (80.3 %)

0.508**

Caucasian

31 (22.8 %)

105 (72.2 %)

0.403**

51 (20.6 %)

196 (79.4 %)

0.440**

BMI (kg/cm2)

25.15 ± 11.12

25.57 ± 2.44

0.356*

29.17 ± 6.40

29.33 ± 5.61

0.844*

Waist circumference (cm)

97.25 ± 15.96

99.30 ± 9.13

0.283*

99.81 ± 14.73

100.27 ± 13.59

0.798*

Diabetes mellitus

15 (23.1 %)

50 (76.9 %)

0.418**

32 (18.8 %)

138 (81.2 %)

0.895**

Metabolic syndrome

28 (19.4 %)

116 (80.6 %)

0.621**

48 (17.8 %)

222 (82.2 %)

0.733**

Cardiovascular disease

19 (22.6 %)

65 (77.4 %)

0.547**

26 (19.8 %)

105 (80.2 %)

0.653**

o Cerebrovascular disease

0 (0.0 %)

20 (100.0 %)

0.016**

13 (28.3 %)

33 (71.7 %)

0.073**

o Coronary disease

13 (29.5 %)

31 (70.5 %)

0.096**

11 (16.9 %)

54 (83.1 %)

0.703**

o Peripheral vascular disease

9 (20.5 %)

35 (79.5 %)

0.976**

10 (20.4 %)

39 (76.9 %)

0.697**

o Congestive Heart Failure

6 (19.4 %)

25 (80.6 %)

0.850**

7 (14.9 %)

40 (85.1 %)

0.480**

Statin use

23 (21.9 %)

82 (78.1 %)

0.551**

38 (19.4 %)

158 (80.6 %)

0.602**

Cholesterol(mmol/L)

3.75 ± 1.01

3.62 ± 0.90

0.470*

4.58 ± 1.06

4.75 ± 1.06

0.175*

HDL-C(mmol/L)

0.97 ± 0.34

1.08 ± 0.46

0.108*

1.15 ± 0.31

1.22 ± 0.35

0.128*

LDL-C(mmol/L)

1.92 ± 0.74

1.82 ± 0.76

0.469*

2.62 ± 0.85

2.79 ± 0.92

0.151*

Triglycerides(mmol/L)

1.98 ± 1.36

1.66 ± 1.14

0.160*

1.84 ± 1.06

1.69 ± 0.90

0.237*

ADMA (uM)

0.95 ± 0.45

1.44 ± 0.96

0.000*

0.58 ± 0.17

0.63 ± 0.28

0.134*

CRP (mg/dL)

1.67 ± 3.52

1.42 ± 3.88

0.711*

0.50 ± 0.72

0.57 ± 0.76

0.468*

  1. *Student’s t test
  2. **Pearson chi-square