Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 4 Demographic and laboratory characteristics of patients according to RRT allocation and ApoE ε4 allele presence

From: Apolipoprotein E polymorphism modulation of asymmetric dimethylarginine in hypertensive patients is determined by renal function

  In RRT   Not in RRT  
  ε4 allele (+) (N = 40) ε4 allele (−) (N = 158) P ε4 allele (+) (N =74) ε4 allele (−) (N = 330) P
Age (years) 52.47 ± 14.97 53.60 ± 14.36 0.669* 62.80 ± 13.36 63.81 ± 11.72 0.511*
Dialysis vintage 38.95 ± 24.24 37.22 ± 27.69 0.697* - -  
Male 25 (21.6 %) 91 (78.4 %) 0.574** 37 (19.7 %) 151 (80.3 %) 0.508**
Caucasian 31 (22.8 %) 105 (72.2 %) 0.403** 51 (20.6 %) 196 (79.4 %) 0.440**
BMI (kg/cm2) 25.15 ± 11.12 25.57 ± 2.44 0.356* 29.17 ± 6.40 29.33 ± 5.61 0.844*
Waist circumference (cm) 97.25 ± 15.96 99.30 ± 9.13 0.283* 99.81 ± 14.73 100.27 ± 13.59 0.798*
Diabetes mellitus 15 (23.1 %) 50 (76.9 %) 0.418** 32 (18.8 %) 138 (81.2 %) 0.895**
Metabolic syndrome 28 (19.4 %) 116 (80.6 %) 0.621** 48 (17.8 %) 222 (82.2 %) 0.733**
Cardiovascular disease 19 (22.6 %) 65 (77.4 %) 0.547** 26 (19.8 %) 105 (80.2 %) 0.653**
o Cerebrovascular disease 0 (0.0 %) 20 (100.0 %) 0.016** 13 (28.3 %) 33 (71.7 %) 0.073**
o Coronary disease 13 (29.5 %) 31 (70.5 %) 0.096** 11 (16.9 %) 54 (83.1 %) 0.703**
o Peripheral vascular disease 9 (20.5 %) 35 (79.5 %) 0.976** 10 (20.4 %) 39 (76.9 %) 0.697**
o Congestive Heart Failure 6 (19.4 %) 25 (80.6 %) 0.850** 7 (14.9 %) 40 (85.1 %) 0.480**
Statin use 23 (21.9 %) 82 (78.1 %) 0.551** 38 (19.4 %) 158 (80.6 %) 0.602**
Cholesterol(mmol/L) 3.75 ± 1.01 3.62 ± 0.90 0.470* 4.58 ± 1.06 4.75 ± 1.06 0.175*
HDL-C(mmol/L) 0.97 ± 0.34 1.08 ± 0.46 0.108* 1.15 ± 0.31 1.22 ± 0.35 0.128*
LDL-C(mmol/L) 1.92 ± 0.74 1.82 ± 0.76 0.469* 2.62 ± 0.85 2.79 ± 0.92 0.151*
Triglycerides(mmol/L) 1.98 ± 1.36 1.66 ± 1.14 0.160* 1.84 ± 1.06 1.69 ± 0.90 0.237*
ADMA (uM) 0.95 ± 0.45 1.44 ± 0.96 0.000* 0.58 ± 0.17 0.63 ± 0.28 0.134*
CRP (mg/dL) 1.67 ± 3.52 1.42 ± 3.88 0.711* 0.50 ± 0.72 0.57 ± 0.76 0.468*
  1. *Student’s t test
  2. **Pearson chi-square