Fig. 7
From: Homology modeling and docking studies of ENPP4: a BCG activated tumoricidal macrophage protein
ENPP4 has tumoricidal activity against MCA207 cells. a Antibodies against ENPP4 influenced the tumoricidal activity of macrophages. Negative control cells exhibited no cytotoxic activity, whereas BCG-activated macrophages exhibited a cytotoxicity of 50 %. Blocking ENPP4 on BCG-activated macrophages decreased the cytotoxicity to 35.1 %. *, P < 0.05 compared with positive control. b ENPP4 protein inhibited the proliferation of MCA207 cells in a dose-dependent manner. *, P < 0.05 compared with negative control