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Table 5 Multivariate analysis of obtained results

From: Markers of increased atherosclerotic risk in patients with chronic kidney disease: a preliminary study

Table 5

p

OR

95.0 % CI range

The presence of heart failure

Chronic kidney disease

0,030

4,625

(1,161 - 18,429)

Osteopontin

0,045

0,979

(0.960 - 1,000)

Age

0,010

1,074

(1,017 - 1,135)

(independent of osteocalcin, osteoprotegerin, fetuin, gender)

Age

0,004

1,083

(1,026 - 1,142)

MMP-2

0,048

1,004

(1,000 - 1,009)

(independent of gender, chronic kidney disease, MMP-9, TIMP-1, TIMP-2)

Age

0,001

1,109

(1,046 - 1,176)

Chronic kidney disease

0,038

5,361

(1,098 - 26,176)

(independent of gender, MGP, ANGII, chronic kidney disease)

Age

0,004

1,083

(1,026 - 1,143)

Chronic kidney disease

0,013

7,449

(1,532 - 36,222)

AIP

0,053

8,694

(0,977 - 77,396)

(independent of gender, ABCA1, ABCG1, non-HDL cholesterol, urea)

Phosphates above normal level

Osteoprotegerin

0,025

1,163

(1,019 - 1,328)

(independent of osteocalcin, osteopontin, fetuin, age, gender)

Presence of hypertension

Chronic kidney disease

0,007

8,202

(1,790 - 37,584)

(independent of age, gender, MMP-2, MMP-9, TIMP-1, TIMP-2)

The presence of atherosclerosis

Gender

0,017

0,223

(0,065 - 0,769)

(independent of age, chronic kidney disease, MMP-2, MMP-9, TIMP-1, TIMP-2)

Gender

0,045

0,301

(0,093 - 0,971)

(independent of age, chronic kidney disease, MGP, GM-CSF, ANGII

Lipid disorders

Non-HDL cholesterol

0,007

1,881

(1,186 - 2,983)

(independent of age, gender, chronic kidney disease, ABCA1, ABCG1, AIP, urea)

AIP – high risk

TCh

0,000

0,019

0,003 – 0,138

Non-HDL cholesterol

0,000

110,134

11,416 - 1062,535

(independent of age, gender, chronic kidney disease, ABCA1, ABCG1, urea)

  1. Abbreviations: MMP-2 matrix metalloproteinase 2, MMP-9 matrix metalloproteinase 9, TIMP-1 & TIMP-2 tissue inhibitor of metalloproteinases-1&2, MGP matrix Gla protein, AngII angiotensin II, GM-CSF granulocyte-macrophage colony-stimulating factor, AIP atherogenic index of plasma, TCh total cholesterol, ABCA1 ATP binding cassette subfamily A member 1, ABCG1 ATP-binding cassette sub-family G member 1