| |
Control group
|
HFD group
|
Acipimox group
|
|---|
|
Weeks
|
8 w
|
16 w
|
24 w
|
8 w
|
16 w
|
24 w
|
8 w
|
16 w
|
24 w
|
|
Weight (g)
|
419.7 ± 8.6
|
500.5 ± 9.8
|
582.6 ± 16.5
|
470.2 ± 17.8
|
646.2 ± 15.5**
|
690.5 ± 29.5*
|
456.0 ± 16.6
|
615.3 ± 22.2**
|
682.7 ± 20.2*
|
|
Visceral fat (g)
|
14.04 ± 0.79
|
17.43 ± 1.26
|
20.06 ± 1.78
|
24.71 ± 1.04**
|
52.97 ± 4.16**
|
73.44 ± 5.15**#
|
24.86 ± 0.67**
|
46.03 ± 4.22**
|
56.58 ± 3.39**
|
|
Visceral fat/weight (%)
|
3.5 ± 0.2
|
3.4 ± 0.3
|
3.6 ± 0.3
|
5.3 ± 0.3**
|
8.3 ± 0.7**
|
10.9 ± 0.5**##
|
5.5 ± 0.4**
|
7.5 ± 0.7**
|
8.7 ± 0.4**
|
|
Liver/body weight (%)
|
2.7 ± 0.1
|
2.5 ± 0.1
|
2.6 ± 0.1
|
3.2 ± 0.1*
|
3.3 ± 0.2*
|
3.1 ± 0.1**
|
3.1 ± 0.1*
|
3.1 ± 0.1*
|
3.0 ± 0.1*
|
- Data are shown as means ± SEM. *
p < 0.05 versus the corresponding Control group; **
p < 0.01 versus the corresponding Control group; #
p < 0.05 versus the corresponding Acipimox group; ##
p < 0.01 versus the corresponding Acipimox group; HFD: high-fat diet
