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Table 4 Values of hepatic MDA and GSH-Px in the studied groups

From: Free fatty acids, not triglycerides, are associated with non-alcoholic liver injury progression in high fat diet induced obese rats

 

Control group

HFD group

Acipimox group

Weeks

8 w

16 w

24 w

8 w

16 w

24 w

8 w

16 w

24 w

hepatic MDA (nmol/mg)

1.59 ± 0.19

2.27 ± 0.30

2.41 ± 0.39

2.17 ± 0.21

5.65 ± 0.36**#

7.15 ± 0.51**##

2.01 ± 0.23

4.15 ± 0.28**

3.62 ± 0.52

hepatic GSH-Px (U/mg)

691.0 ± 31.2

674.1 ± 48.5

606.7 ± 36.2

471.5 ± 42.8*

463.0 ± 26.9*

504.4 ± 19.7

465.8 ± 56.4*

514.8 ± 45.4*

561.1 ± 54.6

  1. Data are shown as means ± SEM. * p < 0.05 versus the corresponding control group; ** p < 0.01 versus the corresponding Control group; # p < 0.05 versus the corresponding Acipimox group; ## p < 0.01 versus the corresponding Acipimox group, HFD high-fat diet, MDA malondialdehyde, GSH-Px glutathione peroxidase