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Table 4 Values of hepatic MDA and GSH-Px in the studied groups

From: Free fatty acids, not triglycerides, are associated with non-alcoholic liver injury progression in high fat diet induced obese rats

  Control group HFD group Acipimox group
Weeks 8 w 16 w 24 w 8 w 16 w 24 w 8 w 16 w 24 w
hepatic MDA (nmol/mg) 1.59 ± 0.19 2.27 ± 0.30 2.41 ± 0.39 2.17 ± 0.21 5.65 ± 0.36**# 7.15 ± 0.51**## 2.01 ± 0.23 4.15 ± 0.28** 3.62 ± 0.52
hepatic GSH-Px (U/mg) 691.0 ± 31.2 674.1 ± 48.5 606.7 ± 36.2 471.5 ± 42.8* 463.0 ± 26.9* 504.4 ± 19.7 465.8 ± 56.4* 514.8 ± 45.4* 561.1 ± 54.6
  1. Data are shown as means ± SEM. * p < 0.05 versus the corresponding control group; ** p < 0.01 versus the corresponding Control group; # p < 0.05 versus the corresponding Acipimox group; ## p < 0.01 versus the corresponding Acipimox group, HFD high-fat diet, MDA malondialdehyde, GSH-Px glutathione peroxidase