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Table 2 Change of clinical and laboratory characteristics before and after ALA treatment

From: α-Linolenic acid increases the G0/G1 switch gene 2 mRNA expression in peripheral blood mononuclear cells from obese patients: a pilot study

Parameters

ALA (n = 14)

 

Control (n = 12)

 

Baseline

After 12 weeks

p

Baseline

After 12 weeks

p

Age (years)

48.6 ± 6.8

  

49.3 ± 4.8

  

Body weight (kg)

93.6 ± 6.6

89.8 ± 5.8

0.116

95.3 ± 6.6

92.6 ± 6.7

0.335

BMI (kg/m2)

32.3 ± 1.2

31.0 ± 1.3

0.009*

32.7 ± 1.0

31.8 ± 0.8

0.018*

TC (mmol/L)

5.01 ± 0.48

4.79 ± 0.42

0.209

5.17 ± 0.45

5.01 ± 0.41

0.381

TG (mmol/L)

3.59 ± 0.65

1.73 ± 0.31

<0.0001*

3.73 ± 0.63

2.63 ± 0.54

0.048*

FFA (μmol/L)

655 ± 324

469 ± 29

<0.0001*

662 ± 28

501 ± 28

<0.0001*

Glycerol (μmol/L)

1505 ± 27

1028 ± 82

<0.0001*

1538 ± 83

1201 ± 94

<0.0001*

IL-6 (ng/L)

2.34 ± 0.14

1.53 ± 0.14

<0.0001*

2.37 ± 0.15

1.87 ± 0.12

<0.0001*

TNF-α (ng/L)

1.92 ± 0.14

1.28 ± 0.10

<0.0001*

1.92 ± 0.16

1.63 ± 0.15

<0.0001*

  1. Data are means ± SD
  2. Baseline vs After 12 weeks, two-sample t test, *p < 0.05
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Lipids in Health and Disease

ISSN: 1476-511X