Fig. 1
From: Rapamycin up-regulates triglycerides in hepatocytes by down-regulating Prox1
Rapamycin increases the amount of triglycerides in HepG2 cells but does not affect cellular proliferation. a HepG2 cells were cultured in low-serum media (1 % FBS) with or without rapamycin (RAPA, 10 nM). After 48 h, cell proliferation was measured by WST-1 assay. Mock: untreated control group. b HepG2 cells treated with or without rapamycin were harvest after 48 h and intracellular triglycerides was measured by thin layer chromatography (TLC). TG: triglycerides, Cho: cholesterol. c Relative triglycerides were analyzed using the Image J program (p < 0.05)