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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Rapamycin up-regulates triglycerides in hepatocytes by down-regulating Prox1

Fig. 4

Prox1 in mouse liver is down-regulated by rapamycin. a Rapamycin or vehicle was injected daily into mouse (n = 5/group) intraperitoneally for 2 weeks. Total lipids and proteins were extracted from liver and used for TLC and western blot analysis, respectively. TG: triglycerides, Cho: cholesterol. b Relative triglycerides compared to cholesterol shows a statistically significant increase in quantity in rapamycin-treated tissues (p < 0.05). c Western blot analysis shows that rapamycin down-regulated prox1 expression. d The expression of prox1 was analyzed by comparing with β-actin, which shows a statistically significant down-regulation of prox1 expression by rapamycin (p < 0.01)

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