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Table 2 The information for three opioids used for dose conversion

From: Opioid doses required for pain management in lung cancer patients with different cholesterol levels: negative correlation between opioid doses and cholesterol levels

 

Fentanyl

Morphine sulfate

Oxycodone hydrochloride

Formula

Transdermal patch

Controlled-release tablets

Controlled-release tablets

Minimal dose

25 μg/h per patch

10 mg per tablet

5 mg per tablet

Initial dose

25 μg/h

30 mg/day

10 mg/day

Initial dose converted to oxycodone

10 mg/day

10 mg/day

Not necessary

Initial dose equivalent to oxycodone

7.5 ~ 20 mg/day

10 ~ 20 mg/day

Not necessary

  1. Basing on the NCCN guidelines and previous reports, doses of morphine and fentanyl in were converted to equivalent doses of oxycodone