Fig. 4
From: MiR-106b exhibits an anti-angiogenic function by inhibiting STAT3 expression in endothelial cells
a-l QRT-PCR results of different candidate genes and western-blot results of STAT3 protein expression among groups under different treatments. a-h VEGFA, JAK1 and MAPK14 expression levels are not significantly affected by miR-106b up or down regulation in HUVECs (P >0.05, n = 6). Meanwhile, over-expressed miR-106b represses STAT3 mRNA expression in HUVECs, while miR-106b inhibition lead to an increase in STAT3 expression. Results are shown as mean ± SEM representative of at least three independent experiments. **P <0.05, n = 6. i-l Identical to the outcome obtained from qRT-PCR, miR-106b mimic transfection inhibits STAT3 expression while miR-106b inhibitor transfection enhances STAT3 expression. Data are shown as mean ± SEM representative of at least three independent experiments. **P <0.05, n = 6