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Table 3 Linear regression analyses of baseline values and percent changes in clinical factors affecting the percent change in LDL-C levels

From: Serum CETP status is independently associated with reduction rates in LDL-C in pitavastatin-treated diabetic patients and possible involvement of LXR in its association

  Univariate Multivariate
n βa 95 % CIb p n βc 95 % CIb p
BMI (kg/m2) 46 0.17 −0.39 ~ 1.39 0.27d     
Gender (Male = 1, Female = 2) 47 −0.13 −11.5 ~ 4.59 0.39     
Age (year) 47 −0.24 −0.72 ~ 0.06 <0. 1 44 −0.07 −0.55 ~ 0.38 0.7
Body weight (kg) 47 0.3 0.02 ~ 0.52 0.04 44 0.07 −0.24 ~ 0.36 0.68
Abdominal girth (cm) 45 0.11 −0.28 ~ 0.59 0.47     
HbA1c (%) 47 0.08 −3.57 ~ 6.38 0.57     
Uric acid (mg/dL) 47 0.05 −2.3 ~ 3.26 0.74     
TC (mg/dL) 47 −0.37 −0.29 ~ −0.04 0.011 44 -0.39 −0.30 ~ −0.05 0.009
LDL-C (mg/dL) 47 −0.21 −0.22 ~ 0.04 0.15e     
TG (mg/dL) 47 −0.1 −0.07 ~ 0.04 0.5     
HDL-C (mg/dL) 47 −0.32 −0.56 ~ −0.03 0.03 44 −0.16 −0.42 ~ 0.13 0.29
sd LDL-C (mg/dL) 47 −0.29 −0.43 ~ 0.01 0.04e     
ApoA-I (mg/dL) 47 −0.28 −0.29 ~ 0.003 0.05f     
CETP (μg/mL) 44 0.38 2.09 ~ 15.69 0.01 44 0.41 2.91 ~ 16.5 0.006
Pioglitazone use 47 −0.02 −12.1 ~ 10.63 0.9     
Change in Body weight (%) 47 0.19 −0.57 ~ 2.66 0.2 43 0.36 0.44 ~ 3.64 0.01
Change in HbA1c (%) 47 −0.009 −0.56 ~ 0.52 0.95     
Change in Uric acid (%) 47 0.14 −0.15 ~ 0.43 0.33     
Change in TG (%) 46 0.22 −0.02 ~ 0.12 0.15 43 0.17 −0.02 ~ 0.10 0.2
Change in HDL-C (%) 47 −0.07 −0.47 ~ 0.29 0.64     
Change in ApoA-I (%) 46 0.06 −0.48 ~ 0.71 0.71     
Change in CETP (%) 44 0.44 0.12 ~ 0.52 0.003 43 0.57 0.21 ~ 0.60 0.0001
  1. astandard regression coefficient
  2. bconfidence interval
  3. cstandard partial regression coefficient
  4. dBMI was excluded from multivariate analysis, since colinearity between BMI and body weight was found
  5. eLDL-C and sd LDL-C were excluded from multivariate analysis, since colinearity among TC, LDL-C and sd LDL-C was found
  6. fApoA-I was excluded from multivariate analysis, since colinearity between HDL-C and ApoA-I was found
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Lipids in Health and Disease

ISSN: 1476-511X