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Table 3 Genotype distribution in obese vs Non-obese subjects

From: SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects

  Obese (%) Non-obese (%) Odds ratio (95 CI) P-value
rs3480 A/G     
GG 49 (17.2) 66 (25.8) 0.48 (0.28–0.79) 0.005
AG 136 (47.7) 117 (45.7) 0.76 (0.50–1.15) 0.20
AA 100 (35.1) 73 (28.5) 1.0 1.0
rs1746661 G/T     
TT 22 (8.7) 18 (7.0) 1.30 (0.64–2.6) 0.47
GT 83 (32.7) 83 (32.4) 1.04 (0.69–1.56) 0.82
GG 149 (59.7) 155 (60.5) 1.0 1.0
rs1298190 A/G     
GG 5 (1.8) 3 (1.2) 1.25 (0.26–6.0) 0.77
AG 64 (22.5) 63 (24.5) 0.88 (0.58–1.35) 0.57
AA 216 (75.8 191 (74.3) 1.0 1.0
rs1570569 G/T     
TT 19 (6.6) 13 (5.1) 1.33 (0.60–2.92) 0.47
GT 100 (35) 89 (34.8) 1.06 (0.72–1.56) 0.74
GG 167 (58.4) 154 (60.2) 1.0 1.0
  1. Note: The genotype distribution of rs3480 (A/G), rs1746661 (G/T), rs1298190 (A/G) and rs1570569 (G/T) variants of FNDC5 gene. Genotype frequency differences between obese and non-obese were tested for each SNP using Chi-square test. Odds ratios (ORs) and 95 % confidence intervals for genotypes were calculated using multinomial logistic regression analyses using obesity as dependent variable adjusted for age, gender and T2DM. Significance was set at p < 0.05. The most common genotype was used as the reference. The variant rs7246344 (A/G) was excluded from analysis due to low rare genotype frequency
  2. Bold means reference value